Gallbladder Metastasis From Renal Cell Carcinoma, an Extremely Rare Neoplastic Dissemination Location

Quiroz, Julio César Zevallos; Pérez, Aintzane Lizarazu; Gorrochategui, Esther Guisasola; Gómez, Miguel Ángel Medrano; Agüero, Raúl Jiménez

doi:10.1016/j.cireng.2012.02.006

Cited by 4 publications

(1 citation statement)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Ultrasonography (US) generally is the first diagnostic tool in gallbladder tumors. Metastases can appear under different hyperechoic masses bigger than 1cm in diameter, close to the gallbladder wall without posterior acoustic shadowing [49][50][51][52][53][54][55][56][57][58][59][60][61][62][63][64][65][66][67] . Color-Doppler is an important complementary technique since the detection of flow signals rules out biliary sludge and cholesterol polyps, and indicates an expansive lesion [42] .…”

Section: Diagnosismentioning

confidence: 99%

Gallbladder’s Clear Cell Renal Cell Carcinoma Metastasis: A Systematic Review of the Literature

2016

Cancer Cell Microenviron

View full text Add to dashboard Cite

Renal cell carcinoma (RCC) represents 2% of all cancers, being the clear cell subtype the most common among renal tumors (70-80%). RCC is well known for its capacity to metastasize in an early stage of the disease, gallbladder metastases are considered extremely rare. The symptomatology goes from asymptomatic to cholecystitis like-symptoms. Ultrasonography, may be often, the first diagnostic tool, tumors can appear under different hyperechoic masses without acoustic shadowing. Metastasectomy has gained a wide consensus because of the possibility of extending survival, keeping in mind the importance of selection of the ideal candidate for it. The surgical procedure will be chosen upon the extend of the disease, it may go from a simple cholecystectomy to a cholecystectomy associated with a wedge/right hepatic lobectomy for curative purposes. We performed a systematic review of 77 cases of gallbladder's clear cell renal cell carcinoma metastasis published from 1963 up to date, analyzing the symptomatology at presentation, diagnosis, treatment, prognosis, and surgical procedures.

show abstract

Section: Diagnosismentioning

confidence: 99%

Gallbladder’s Clear Cell Renal Cell Carcinoma Metastasis: A Systematic Review of the Literature

2016

Cancer Cell Microenviron

View full text Add to dashboard Cite

show abstract

Metachronous gallbladder metastasis from renal cell carcinoma—a rare clinical manifestation

Mrak

Lackner

Mischinger

et al. 2016

Wien Klin Wochenschr

View full text Add to dashboard Cite

Renal cell carcinoma (RCC) represents a rare tumor entity accounting for approximately 3 % of all malignancies in the adult population. Approximately 30 % of all patients suffering from RCC develop metastases after nephrectomy and another 30 % of patients suffer from synchronous metastases at the date of diagnosis. Gallbladder metastases represent an extremely rare clinical condition and up to date there are only 35 published cases of gallbladder metastasis from RCC. Surgical resection should be the treatment of choice in any case based on the reported data in literature. In spite of the small series of cases, survival can be improved even in patients suffering from additional sites of metastases.

show abstract

Metastatic polyp of the gallbladder from renal cell carcinoma

et al. 2017

View full text Add to dashboard Cite

BackgroundGallbladder metastasis from renal cell carcinoma (RCC) is extremely rare. The purpose of this study is to clarify the characteristics of metastatic RCC to gallbladder.MethodsThe pooled data for analysis were collected from the case of metastatic RCC to gallbladder encountered by our institution along with sporadic cases reported in literature from 1991 to 2015.ResultsA total of 50 cases of metastatic RCC to gallbladder were recruited for study. Fifty-seven percentage of the primary RCC was from the right kidney and 43% from the left. The median interval between diagnoses of primary and metastatic RCC to gallbladder was 36 months, with the longest duration up to 324 months. Most (70%) were asymptomatic. The size of metastatic RCC to gallbladder ranged from 0.8 cm to 9 cm, with median of 2.6 cm. Majority (91%) of the metastatic RCCs presented as a polypoid mass with narrow stalk, and 82% were hypervascular lesion. The overall 1 year, 3 year and 5 year survival rate was 91.5%, 76.2% and 59.3% respectively, with a median of 26.5 months. Number of the metastatic site, timing of gallbladder metastasis, symptom, tumor size and operation type of cholecystectomy seemed to have no impact on survival.ConclusionsMetastatic RCC to the gallbladder should be taken into account for a gallbladder polypoid mass with narrow hypervascular stalk during the diagnosis and/or follow-up of primary RCC. Gallbladder metastasis from RCC is not necessarily to be an advanced stage with poor outcome, and cholecystectomy is recommended whenever possible.

show abstract

Gallbladder Metastasis From Renal Cell Carcinoma, an Extremely Rare Neoplastic Dissemination Location

Cited by 4 publications

References 5 publications

Gallbladder’s Clear Cell Renal Cell Carcinoma Metastasis: A Systematic Review of the Literature

Gallbladder’s Clear Cell Renal Cell Carcinoma Metastasis: A Systematic Review of the Literature

Metachronous gallbladder metastasis from renal cell carcinoma—a rare clinical manifestation

Metastatic polyp of the gallbladder from renal cell carcinoma

Contact Info

Product

Resources

About