Gallbladder lymphoma

Viswanathan, Srinivas R.; Khalpey, Zain; Ashley, Stanley W.

doi:10.1007/s12032-010-9535-y

Cited by 8 publications

(5 citation statements)

References 4 publications

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“…The tumor size and appearance are not typical. Submucosal thickening with few atypical cells or a small (0.5-4 cm) tumor with discrete boundaries or a polypoid transformation with neoplastic lymphoproliferative cells have all been described [9][10][11]. We first reported an unusual appearance of a bulky lymphoid tumor (14 cm) attached to the liver bed and hilum.…”

Section: Discussionmentioning

confidence: 99%

Primary Large Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma of the Gallbladder

Papamichail¹,

Dimitrokallis²,

Gogolou³

et al. 2022

Cureus

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Primary lymphoma of the gallbladder (GB) is a rare condition, and very few cases have been reported so far. Diagnosis is usually made after surgery of suspicious GB mass, which is often difficult to differentiate from GB carcinoma. The GB wall does not contain lymphoid tissue, and tumors arise at the submucosal layer. Stone disease and chronic inflammation may contribute to its pathogenesis. Treatment consists of surgical resection followed by adjuvant therapy in selected cases. We present a case of an unusual, large-sized mucosa-associated lymphoid tissue (MALT) lymphoma of the GB.

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Section: Discussionmentioning

confidence: 99%

Primary Large Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma of the Gallbladder

Papamichail¹,

Dimitrokallis²,

Gogolou³

et al. 2022

Cureus

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“…The histological types were frequently reported as mucosa-associated lymphoid tissue (MALT) lymphoma [ 9 , 10 ], DLBCL [ 7 , 11 ], IVLBCL [ 6 , 12 ] and follicular lymphoma [ 13 , 14 ], and there were rare cases with the coexistence of DLBCL and MALT lymphoma [ 15 ], and malignant lymphoma and gallbladder adenocarcinoma [ 16 ]. We compare the clinical features of reported cases of gallbladder MALT lymphoma (n = 13) and gallbladder DLBCL (n = 15) in Table 2 to evaluate the difference in characteristics between the two subtypes, which are considered to be common in gastrointestinal malignant lymphoma, including the stomach.…”

Section: Discussionmentioning

confidence: 99%

Diffuse large B-cell lymphoma of the gallbladder arised 8 years after malignant lymphoma of the right testis: A case report and literature review

Kai

Hamada

Hiyoshi

et al. 2020

International Journal of Surgery Case Reports

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Highlights Gallbladder involvement by lymphoma is extremely rare, and only 68 cases have been reported in the English literature so far. We experienced a case of diffuse large B-cell lymphoma (DLBCL) of the gallbladder arising 8 years after DLBCL of the right testis. We compiled and analysed reported cases in terms of background, symptoms, imaging findings, and prognosis. DLBCL was significantly more involved in other organs simultaneously or heterochronously in contrast of MALT lymphoma ( p = 0.004). Gallbladder lymphoma should be added to the differential diagnosis of gallbladder tumours.

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“…Gallbladder involvement by large cell NHL was diagnosed in a patient witch Richter's syndrome (Maryniak and Konecki 1991). The time interval between diagnosis of the primary NHL and its later manifestations in the gallbladder may be long, e.g., 12 years in a patient with follicular NHL (Viswanathan et al 2011). Very rarely, the gallbladder is the site of reactive lymphocytic proliferations forming a mass, i.e., pseudolymphoma (Hussain et al 1976).…”

Section: Differential Diagnosismentioning

confidence: 99%

Melanocytic, Neuroectodermal, Germ Cell, Rhabdoid, Perivascular Epithelioid Cell, Hemolymphatic, and Metastatic Tumors of the Gallbladder

Zimmermann¹

2016

Tumors and Tumor-Like Lesions of the Hepatobiliary Tract

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The gallbladder is involved by a wide variety of non-epithelial tumors, apart from mesenchymal neoplasms. Visceral malignant melanoma develops in the biliary tract, including the gallbladder. As both primary and metastatic gallbladder melanomas may show similar of the same growth patterns, the differential diagnosis between these two conditions is often difficult. Primary gallbladder melanoma is more likely if the tumor shows a polypoid or lobulated and in particular papillary growth pattern, is a solitary lesion, and is associated with junctional activity in the adjacent mucosa. In contrast, metastatic lesions are more commonly multiple, flat, and without junctional changes. Apart from neuroendocrine tumors, other neuroectodermal neoplasms can develop as primary tumors in the gallbladder. Rare primary neoplasms in this organ include germ cell tumors, rhabdoid tumors, perivascular epithelioid cell tumors, and hemolymphatic neoplasms. Apart from malignant melanoma, numerous other malignancies can metastasize to the gallbladder, renal cell carcinoma being a particularly common metastasizing tumor. Malignant Melanoma of the Gallbladder Pathogenic Pathways Few melanocytes are present in the normal gallbladder mucosa, and it has been suggested that malignant melanomas take their origin from these cells that have spread from the neural crest to the gallbladder during oncogenesis. Primitive Neuroectodermal Tumor (PNET) of the Gallbladder Differential Diagnosis Differential diagnosis on conventionally stained sections mainly includes other small cell tumors occurring in the gallbladder, e.g., small cell carcinoma or lymphoma. Differential Diagnosis Gallbladder paraganglioma may occur as a component of multiple paragangliomas, involving the common bile duct and the liver in addition to the gallbladder (Ferrell et al. 1990).

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Gallbladder lymphoma

Cited by 8 publications

References 4 publications

Primary Large Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma of the Gallbladder

Primary Large Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma of the Gallbladder

Diffuse large B-cell lymphoma of the gallbladder arised 8 years after malignant lymphoma of the right testis: A case report and literature review

Melanocytic, Neuroectodermal, Germ Cell, Rhabdoid, Perivascular Epithelioid Cell, Hemolymphatic, and Metastatic Tumors of the Gallbladder

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