Gallbladder Lesions Identified on Ultrasound. Lessons from the Last 10 Years

Konstantinidis, Ioannis T.; Bajpai, Surabhi; Kambadakone, Avinash; Tanabe, Kenneth K.; Berger, David L.; Zheng, Hui; Sahani, Dushyant V.; Lauwers, Gregory Y.; Castillo, Carlos Fernández‐del; Warshaw, Andrew L.; Ferrone, Cristina R.

doi:10.1007/s11605-011-1696-2

Cited by 44 publications

(23 citation statements)

References 20 publications

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“…According to the management algorithm, which was determined by a review of the literature, management of gallbladder polyps primarily relies on the size of the lesion (Fig 12) (1, 3,17,44,60,[62][63][64][65][66][67][68][69][70][71]. Two large series confirmed that a size larger than 10 mm is the best indicator of malignancy and warrants cholecystectomy (60,61).…”

Section: Management Algorithmmentioning

confidence: 99%

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Polypoid Lesions of the Gallbladder: Disease Spectrum with Pathologic Correlation

Mellnick¹,

Menias

Sandrasegaran³

et al. 2015

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Gallbladder polyps are seen on as many as 7% of gallbladder ultrasonographic images. The differential diagnosis for a polypoid gallbladder mass is wide and includes pseudotumors, as well as benign and malignant tumors. Tumefactive sludge may be mistaken for a gallbladder polyp. Pseudotumors include cholesterol polyps, adenomyomatosis, and inflammatory polyps, and they occur in that order of frequency. The most common benign and malignant tumors are adenomas and primary adenocarcinoma, respectively. Polyp size, shape, and other ancillary imaging findings, such as a wide base, wall thickening, and coexistent gallstones, are pertinent items to report when gallbladder polyps are discovered. These findings, as well as patient age and risk factors for gallbladder cancer, guide clinical decision making. Symptomatic polyps without other cause for symptoms, an age over 50 years, and the presence of gallstones are generally considered indications for cholecystectomy. Incidentally noted pedunculated polyps smaller than 5 mm generally do not require follow-up. Polyps that are 6-10 mm require follow-up, although neither the frequency nor the length of follow-up has been established. Polyps that are larger than 10 mm are typically excised, although lower size thresholds for cholecystectomy may be considered for patients with increased risk for gallbladder carcinoma, such as patients with primary sclerosing cholangitis.

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Section: Management Algorithmmentioning

confidence: 99%

“…Management of polyps that measure 5 mm or less is also not clearly established. A study found that, among patients with sub-5-mm polyps at preoperative US, no focal lesion was seen in cholecystectomy specimens from more than 80% of patients (66). Another study reported that 24% of sub-5-mm polyps were not seen at follow-up US (63).…”

Section: Management Algorithmmentioning

confidence: 99%

Polypoid Lesions of the Gallbladder: Disease Spectrum with Pathologic Correlation

Mellnick¹,

Menias

Sandrasegaran³

et al. 2015

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“…The suggested predictive factors of a malignant GB polyp include size (≥10 mm), solitary lesion, age (≥50-60 years), increased size of polyp during follow-up, concurrent gallstones, sessile lesions, and gallbladder wall thickening [1,17,18]. In our study, the significant predictive factors of a Note: ROI = region of interest neoplastic polyp were age (≥57 years), size (≥15 mm), the absence of hyperechoic foci, an irregular margin, a sessile shape, a single polyp, and the presence of adjacent GB wall thickening by univariate analysis.…”

Section: Discussionmentioning

confidence: 99%

US characteristics for the prediction of neoplasm in gallbladder polyps 10 mm or larger

et al. 2015

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“…Color Dopple ultrasound distinguishes gallbladder carcinoma from intragallbladder cholestasis according to the blood flow signal. A high-speed blood flow indicates gallbladder carcinoma with the sensitivity of 83.9% and the specificity of 80.5% [10]. CT functions in the diagnosis of gallbladder carcinoma in the distinguishing of it from chronic cholecystitis and gallbladder polyps, the clinical staging and the judgment about resectability.…”

Section: Diagnosismentioning

confidence: 99%

Surgical Treatment and Prognosis Analysis of Primary Carcinoma of Gallbladder

Fang¹

2017

CMR

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Abstract:To discuss the effects of different treatment methods on the prognosis of primary carcinoma of gallbladder (PCG) patients. The clinical statistics of 99 cases of PCG patients were retrospectively analyzed, and the prognosis multivariate analysis was performed. Results: 52% of the patients suffered from PCG and gallstones simultaneously, and 82.8% (82/99) of the patients were diagnosed as PCG before surgeries. 86 cases of patients were subjected to routine exploratory surgeryies, and the radical resection rate was 33.72% (29/86). The overall 5-year survival rate was 6.28%, and the 1-year, 3-year and 5-year survival rates of the radical resection group were 78.43%, 48.49% and 23.77%, respectively. The results were significantly different from those of the palliative surgery group, the exploratory laparotomy group and the non-surgical group. The multivariate analysis of Cox model reveals that surgical method was significantly correlated with the invasion depth of tumor and the prognosis of gallbladder carcinoma. The treatment efficacy of PCG might be improved by increasing the early diagnosis rate and performing radical resection which are accompanied by radiotherapy and chemotherapy.

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Gallbladder Lesions Identified on Ultrasound. Lessons from the Last 10 Years

Cited by 44 publications

References 20 publications

Polypoid Lesions of the Gallbladder: Disease Spectrum with Pathologic Correlation

Polypoid Lesions of the Gallbladder: Disease Spectrum with Pathologic Correlation

US characteristics for the prediction of neoplasm in gallbladder polyps 10 mm or larger

Surgical Treatment and Prognosis Analysis of Primary Carcinoma of Gallbladder

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