Gallbladder Cystadenoma and Common Bile Duct Obstruction

Abstract

Cystadenomas are usually found in the extra-hepatic bile ducts in conjunction with multilocular cysts in the liver. Cystadenoma of the gallbladder itself is a rare finding, cited only once in the literature as the cause of extrinsic obstruction of the common bile duct (5). In this report, we describe the endoscopic retrograde cholangiopancreaticographic (ERCP) detection of intrinsic obstruction of the cystic duct and common bile duct by such a tumor in a 47-yr-old woman.

A Rare Case: Primary Mucinous Cystic Neoplasm of the Gallbladder

“…Microscopically, they are characterized as three different layers. There is a cubic-columnar epithelium layer at the core, a mesenchymal stroma layer resembling ovarian stroma in the middle, and a hyalinized fibrous layer at the exterior (9). Immunhistochemically, estrogen and progesterone receptors may be positive, especially in MCN containing ovarian-like stroma.…”

“…Immunhistochemically, estrogen and progesterone receptors may be positive, especially in MCN containing ovarian-like stroma. In addition, cytokeratin can be positive, and smooth muscle actin may also show strong reactivity (9). However, 10 to 15 percent of cystadenomas lack ovarian stroma.…”

Cystadenoma Originating From the Gallbladder

“…Biliary cystadenomas are very uncommon benign tumors. [1][2][3] They are mostly seen intrahepatically in the biliary system, whereas they might be encountered less frequently in the extrahepatic biliary system as well. 7 They are very rare occurrences in the gallbladder, and there are only a few case reports in the literature.…”

“…7 They are very rare occurrences in the gallbladder, and there are only a few case reports in the literature. 3,8 Because of the risk of cystadenosarcoma, they are removed by excision.…”