Gallbladder carcinoma and chronic cholecystitis: differentiation with two-phase spiral CT

Yun, Eun Joo; Cho, S. G.; Park, S.; Park, S.-W.; Kim, W.-H.; Kim, H.-J.; Suh, Chang Hae

doi:10.1007/s00261-003-0080-4

Cited by 58 publications

(48 citation statements)

References 14 publications

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“…The wall is usually 4 -13 mm in thickness and is often asymmetrically thickened and nodular [2]. The differentiation from chronic cholecystitis is difficult and the presence of a highly enhancing thick inner wall layer is considered more indicative of carcinoma whereas an iso-attenuating thin inner wall layer is indicative of chronic cholecystitis [10]. A hypodense halo representing mural oedema in the thickened GB wall has been described as a helpful sign on CT of cholecystitis rather than carcinoma [2].…”

Section: Discussionmentioning

confidence: 99%

Computed Tomographic Findings in 50 Cases of Gall Bladder Carcinoma

George

Godara²,

Dhagat

et al. 2007

Medical Journal Armed Forces India

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Original Article Introduction C arcinoma of the gall bladder (GB) is the fifth most common malignancy of the gastrointestinal tract and the commonest malignancy of the biliary tree [1,2]. It occurs primarily in the sixth to seventh decade of life and is four to five times more common in women [2,3]. Ultrasonography (USG) and computed tomography (CT) have revolutionized the diagnosis and management of carcinoma GB. Magnetic Resonance Imaging (MRI) is utilized only in inoperable cases with obstructive jaundice for delineation of the biliary tract anatomy in patients considered for palliative stenting [3].USG in patients of carcinoma GB has certain limitations such as interference by bowel gas, limited depth resolution and inadequate visualization of parts of the gallbladder in the region of posterior acoustic shadowing in the presence of calculi. CT scan overcomes these drawbacks and provides definite information regarding invasion of the tumour into the adjacent organs, distant metastasis, delineation of the biliary tree and portal vein involvement. We present our experience of CT findings in 50 histologically proven cases of carcinoma GB. Material and MethodsThis retrospective study reviewed CT examination findings in 50 histopathologically proven (from operative specimen or fine needle aspiration cytology) cases of carcinoma GB over a period of two years. The patients presented with a wide spectrum of complaints ranging from dyspepsia, abdominal pain to clinically palpable lump abdomen and obstructive jaundice. All the patients were subjected to helical CT scan examination on a GE HiSpeed CT/i scanner.The CT protocol of 5mm helical CT sections in the axial plane at table speed of 5 mm/sec (pitch 1.0) with kV 120 and mA 280 was used. Breath-hold periods varied from 10 to 16 seconds with intervening breathing time of 8 seconds. The CT scan technique employed in our patients included a preliminary survey scan of the abdomen from levels of the diaphragm to the iliac crest after orally administered one litre of iodinated contrast (800 ml administered 45 minutes prior to and 200ml given just prior to the scan) for opacification of bowel during customized breath-hold phase. This was followed by repeat evaluation of the abdomen during dynamic intravenous injection of 80 ml of non-ionic iodinated contrast medium (300 mg Iodine/ml) for studying the lesional enhancement and vascular structures. Intravenous contrast medium was administered at the rate of 2 ml/sec using a pressure injector at 150 psi using a scan delay of 30 seconds to commence imaging. Suspected cases of duodenal involvement were subjected to targeted area scanning with patient in right decubitus position. ResultsThere was definite female preponderance with male: female Computed Tomographic Findings in 50 Cases of Gall Bladder CarcinomaLt Col RA George * , Col SC Godara + , Lt Col P Dhagat # , Maj PP Som ** Abstract Background : A retrospective assessment of contrast enhanced computed tomography (CECT) scan findings in histopathologically proven cases of c...

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Section: Discussionmentioning

confidence: 99%

Computed Tomographic Findings in 50 Cases of Gall Bladder Carcinoma

George

Godara²,

Dhagat

et al. 2007

Medical Journal Armed Forces India

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“…GBCA are usually hypodense on unenhanced CT, with up to 40% of lesions showing hypervascular foci of enhancement equal to or greater than that of liver after IV contrast administration (14).…”

Section: Resultsmentioning

confidence: 99%

Correlative Imaging in Gallbladder Carcinoma

Willekens

Goethals

Brussaard

et al. 2014

Journal of the Belgian Society of Radiology

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“…A thin mildly enhancing inner layer and a non enhancing thin outer layer was characteristic of chronic cholecystitis. The presence of two enhancement-layer patterns with low attenuated foci within the inner layer suggesting dilated Rokitansky-Aschoff sinuses indicates the presence of adenomyomatosis [12] .…”

Section: Figurementioning

confidence: 99%

Gall Bladder Carcinoma: Computed Tomographic Findings in 50 cases

Mandal¹

2017

JMSCR

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Gallbladder carcinoma and chronic cholecystitis: differentiation with two-phase spiral CT

Cited by 58 publications

References 14 publications

Computed Tomographic Findings in 50 Cases of Gall Bladder Carcinoma

Computed Tomographic Findings in 50 Cases of Gall Bladder Carcinoma

Correlative Imaging in Gallbladder Carcinoma

Gall Bladder Carcinoma: Computed Tomographic Findings in 50 cases

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