Gallbladder agenesis with a stone in the cystic duct bud

Ishida, Masaharu; Egawa, Shinichi; Takahashi, Yusuke; Kohari, Masato; Ohwada, Yasuo; Unno, Michiaki

doi:10.1007/s00534-007-1236-3

Cited by 9 publications

(6 citation statements)

References 8 publications

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“… 6 In humans, most patients are asymptomatic, but some show clinical signs, including abdominal pain, nausea and jaundice that is sometimes associated with intra- and/or extrahepatic cholelithiasis. 1 , 12 – 17 Dogs with gallbladder agenesis have often been reported in the absence of clinical signs; half of canine cases are asymptomatic and a common clinical finding is increased liver enzyme activity. 2 – 5 In cats, one previous case report documented a cat with gallbladder agenesis diagnosed from ultrasonography and exploratory laparotomy showing clinical signs in association with inflammatory bowel disease, cholangiohepatitis and pancreatitis.…”

Section: Discussionmentioning

confidence: 99%

“… 18 – 20 Previous studies have reported that 25–50% of human gallbladder agenesis presented with clinical symptoms related to choledocholithiasis. 1 , 12 – 17 In cats, congenital anomalies of the biliary tract may be a risk factor for the formation of choleliths, and clinical case reports have described cholelithiasis with congenital duplex gallbladder. 21 , 22 Some congenital malformations with ductal plate malformation have been considered a risk factors for bacterial infection and cholelithiasis.…”

Section: Discussionmentioning

confidence: 99%

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Common bile duct perforation due to choledocholithiasis in a cat with gallbladder agenesis

Noguchi

Iwanaga

Miura

et al. 2023

Journal of Feline Medicine and Surgery Open Reports

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Case summary An 8-year-old neutered male domestic shorthair cat was presented for further investigation of anorexia, vomiting and lethargy. Abdominal ultrasonography and contrast-enhanced CT revealed choledocholithiasis with suspected bacterial peritonitis and non-visualisation of the gallbladder. During surgery, the common bile duct was noted to be perforated, and a cholelith was found in the abdominal cavity. No gallbladder was confirmed during surgery. Three months postoperatively, the cat underwent CT cholangiography and absence of the gallbladder with a vestigial duplicated gallbladder was diagnosed. Relevance and novel information Gallbladder agenesis is extremely rare in cats, with only one previous report, but several dogs have been diagnosed based on CT cholangiography and laparoscopy. This report describes gallbladder agenesis concurrent with choledocholithiasis in an adult cat and represents the first report of CT cholangiography in a cat with gallbladder agenesis.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Common bile duct perforation due to choledocholithiasis in a cat with gallbladder agenesis

Noguchi

Iwanaga

Miura

et al. 2023

Journal of Feline Medicine and Surgery Open Reports

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“…Gotohda et al [5] stated that if the gallbladder is not visualized by imaging techniques, laparoscopy should be performed before laparotomy. However, laparotomy can be avoided and the risk of any possible complications reduced by the laparoscopic surgeon's awareness of the problems posed by this anomaly and a careful review of currently available diagnostic tests [16].…”

Section: Discussionmentioning

confidence: 99%

Agenesis of the gallbladder as a rare misdiagnosis

et al. 2009

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AbstractAnatomic anomalies of the biliary tract are not uncommon, but gallbladder and cystic duct agenesis is rare, with an incidence of 0.01% to 0.04% and a frequency of 0.016% at autopsy. It is usually asymptomatic and discovered incidentally. Although this congenital anomaly is infrequent, it may be encountered in clinical practice; thus, the surgeon should be aware of the associated problems. A correct preoperative diagnosis of this congenital anomaly is difficult to establish because of the nonspecific nature of the symptoms and the relative inaccuracy of the currently available diagnostic tests. Here we report a patient with a preoperative false diagnosis of cholelithiasis that was found on laparoscopy and open surgery to be agenesis of the gallbladder.

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“…Acute gallbladder distension (hydrops) is unusual in pediatric age [ 1 , 2 ]. It may be a consequence of obstruction of the cystic duct caused by gallstones, cholangitis, sclerosing cholangitis, cystic fibrosis [ 3 ], congenital or postoperative biliary malformations [ 4 ], or benign or malignant lesions [ 5 , 6 ]. Laparoscopic cholecystectomy is usually warranted [ 7 – 10 ].…”

Section: Introductionmentioning

confidence: 99%

Conservative Treatment for Cystic Duct Stenosis in a Child

Gasparetto¹,

Giordano²,

Cananzi³

et al. 2013

Case Reports in Hepatology

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Introduction. Few cases of common bile duct stenosis have been reported in the literature, and observations of strictures in the cystic duct are even more rare. Surgical cholecystectomy is the treatment needed in most cases of gallbladder hydrops. This paper describes the diagnosis and successful medical treatment of a rare pediatric case of cystic duct stenosis and gallbladder hydrops. Case Report. A formerly healthy one-year-old girl was admitted with colicky abdominal pain. Blood tests were normal, except for an increase in transaminases. Abdominal ultrasound excluded intestinal intussusception and identified a distended gallbladder with biliary sludge. MR cholangiography revealed a dilated gallbladder containing bile sediment and no detectable cystic duct, while the rest of the intra- and extrahepatic biliary tree and hepatic parenchyma were normal. This evidence was consistent with gallbladder hydrops associated with cystic duct stenosis. The baby was treated with i.v. hydration, corticosteroids, antibiotics, and ursodeoxycholic acid. Her general condition rapidly improved, with no further episodes of abdominal pain and normalization of liver enzymes. This allowed to avoid cholecystectomy, and the child is well 1.5 years after diagnosis. Conclusions. Although cholecystectomy is usually necessary in case of gallbladder hydrops, our experience suggests that surgical procedures can be avoided when the distension is caused by a cystic duct stenosis.

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Gallbladder agenesis with a stone in the cystic duct bud

Cited by 9 publications

References 8 publications

Common bile duct perforation due to choledocholithiasis in a cat with gallbladder agenesis

Common bile duct perforation due to choledocholithiasis in a cat with gallbladder agenesis

Agenesis of the gallbladder as a rare misdiagnosis

Conservative Treatment for Cystic Duct Stenosis in a Child

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