Gall bladder and extrahepatic bile ducts

Kocjan, Gabrijela

doi:10.1016/b978-0-7020-3154-0.00009-0

Cited by 3 publications

(2 citation statements)

References 72 publications

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“…[ 6 ] Chronic cholecystitis demonstrate scant epithelial cells to sheets of tall columnar cells, nuclei oval and basal with fine nuclear chromatin and inconspicuous nucleoli in Pap stain, often described as “matchstick” cells in cytology textbooks. [ 7 ]…”

Section: Resultsmentioning

confidence: 99%

Cytopathological diagnosis of gallbladder mass and mural thickening based on imaging findings: A prospective study of 51 cases

Kumar

Singhal

Agarwal

et al. 2015

J Cytol

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Background:Image-guided fine-needle aspiration cytology (FNAC) serves as first-line diagnostic modalities for the assessment of mural thickening of the gallbladder (GB).Aim:The main objective of the present study was to correlate the diagnostic accuracy of preoperative image-guided FNAC of the thickened GB wall based on imaging findings to arrive at a final diagnosis in a tertiary care center.Materials and Methods:Fifty-seven image-guided fine-needle aspirations (FNAs) were performed from mural thickening of the GB over a period of 4 years and the smears prepared were stained with Leishman and Papanicolaou (Pap) stain. Out of 57 cases, 51 were included in the study for which follow-up histopathology was performed.Result:Out of 51 aspirations, 43 (84.3%) were adequate, 5 (9.8%) were inconclusive, and 3 (5.9%) were inadequate. Among the adequate aspirations, the most common was adenocarcinoma—36 (70.5%). The correlation between confirmatory cytological diagnosis and adequacy was significantly high (P = 0.0001). The overall diagnostic accuracy for adequate aspiration was 95.3%. The common diagnostic pitfalls were necrotic areas, aspiration of reactive hepatocytes adjacent to the GB mass, and mucus islands. No procedural complication was observed in any patient.Conclusions:Image-guided FNAC can be used as a safe, rapid, and successful diagnostic procedure with high sensitivity, specifically for supporting and confirming ultrasonography(USG)/computed tomography (CT) diagnosis of GB mass or mural thickening of the wall.

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Section: Resultsmentioning

confidence: 99%

Cytopathological diagnosis of gallbladder mass and mural thickening based on imaging findings: A prospective study of 51 cases

Kumar

Singhal

Agarwal

et al. 2015

J Cytol

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“…FNAC, being a safe, superior to open biopsy, rapid, cost-effective, and nonsurgical intervention and a daycare investigation procedure, is gaining popularity as a diagnostic modality for GB mass lesions and intra-abdominal lesions. [11] Diffuse mural thickening and single/multiple lesions detected by USG and CT scan are primary indications for FNAC. [12], [13] Precise radiological localization with novel techniques, multiple passes, and well-defined cytological criteria increases the sensitivity of the test to arrive at a definitive diagnosis.…”

Section: Discussion:-mentioning

confidence: 99%

Trend of Avoiding Fnac’s of Gallbladder Even in Carcinoma Gallbladder Endemic. Zone.

Tiwari¹,

Gupta²,

Lal³

et al. 2016

IJAR

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Carcinoma gallbladder (Ca GB) is the most common malignancy of the biliary tract and has high incidence in selected populations worldwide. [1] It is eight times more common in North India than in South India. Carcinoma gallbladder is a common occurrence in the Gangetic plains of the Eastern Uttar Pradesh and Western Bihar regions of India. [2, 3] It affects women 2-6 times more commonly than men and its incidence steadily increases with age. [3] It is rarely discovered at a stage where it can be treated by surgery hence its mean 5-year survival is about 1% despite surgical intervention. [4] USG guided FNAC's of the gallbladder are proving to be safe, reliable, cost effective measure of diagnosing carcinoma at it's earliest. However interventional radiologists are reluctant in performing the percutaneous FNAC's of the gall bladder for fear of causing biliary peritonitis, improper availability of services, and lack of awareness and fear of needle tract recurrence. This proves as a big impediment in early diagnosis and treatment of gallbladder carcinomas. This study is an attempt to throw light on the significance of ultrasound guided FNAC as a useful technique for diagnosis of this condition. It is also an attempt to shed light on the reluctance of surgeons to go for an easy, cheap, cost effective method of diagnosis like FNAC and opt for more cumbersome and expensive laparoscopic/open biopsy. Materials And Methods:-It was a hospital based retrospective study done in Era's Lucknow Medical College and Hospital. Retrospective data of histopathology and cytopathology for 566 gallbladder lesions in the past two years was taken from the records and morphological diagnosis of these cases confirmed. Two pathologists independently analyzed both the histopathological biopsies and cytopathological smears to rule out inter-observer bias. Cytopathological criteria's taken into account for diagnosis were cells in clusters, disorganized sheets, small acini, and single pleomorphic cells. Marked nuclear enlargement, nuclear crowding, molding, irregular nuclear membranes, and high nuclear-cytoplasmic (N:C) ratio and prominent nucleoli permit a definitive diagnosis of malignancy when there is adequate well-preserved material [6] Results:

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Biliary Duct Brushing

Oliveira¹

2017

Encyclopedia of Pathology

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Gall bladder and extrahepatic bile ducts

Cited by 3 publications

References 72 publications

Cytopathological diagnosis of gallbladder mass and mural thickening based on imaging findings: A prospective study of 51 cases

Cytopathological diagnosis of gallbladder mass and mural thickening based on imaging findings: A prospective study of 51 cases

Trend of Avoiding Fnac’s of Gallbladder Even in Carcinoma Gallbladder Endemic. Zone.

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