Galectin‐3 is upregulated in frontotemporal dementia patients with subtype specificity
Sergi Borrego–Écija,
Agnès Pérez‐Millan,
Anna Antonell
et al.
Abstract:INTRODUCTIONNeuroinflammation is a major contributor to the progression of frontotemporal dementia (FTD). Galectin‐3 (Gal‐3), a microglial activation regulator, holds promise as a therapeutic target and potential biomarker. Our study aimed to investigate Gal‐3 levels in patients with FTD and assess its diagnostic potential.METHODSWe examined Gal‐3 levels in brain, serum, and cerebrospinal fluid (CSF) samples of patients with FTD and controls. Multiple linear regressions between Gal‐3 levels and other FTD marke… Show more
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