Galactomannans with novel structures from the lichen Roccella decipiens Darb

Carbonero, Elaine R.; Cordeiro, Lucimara M.C.; Mellinger, Caroline G.; Sassaki, Guilherme L.; Stocker-Wörgötter, Elfriede; Gorin, Philip A.J.; Iacomini, Marcello

doi:10.1016/j.carres.2005.03.022

Cited by 25 publications

(19 citation statements)

References 17 publications

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“…By comparing the results obtained in this study with earlier studies on lichens (Brull et al, 2000;Carbonero et al, 2005; Montai, Woranovicz-Barreira, Huang et al, 1998;Olafsdottir & Ingolfsdottir, 2001;Omarsdottir et al, 2006b;Pereyra, Prieto, Bernabe, & Leal, 2003;Prieto, Ahrazem, Bernabé, & Leal, 2004;Prieto, Leal, Bernabe, & Hawksworth, 2008;Reis, Tischer, Gorin, & Iacomini, 2002;Teixeira, Iacomini, & Gorin, 1995) the structure of colleman is different from the structure of all previously described lichen polysaccharides including the cyanolichen polysaccharides described from Collema leptosporum (Prado et al, 1999), Leptogium azureum (Carbonero et al, 2003) P. canina Fig. 4.…”

Section: Ppm) Between H-1 Of Xylp and H-3 And C-3 Of B-mentioning

confidence: 68%

Structural characterisation of a new O-methylated heteroglycan, colleman, from the cyanolichen Collema flaccidum

Jensen

Petersen

Veselinovic

et al. 2010

Carbohydrate Polymers

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Section: Ppm) Between H-1 Of Xylp and H-3 And C-3 Of B-mentioning

confidence: 68%

Structural characterisation of a new O-methylated heteroglycan, colleman, from the cyanolichen Collema flaccidum

Jensen

Petersen

Veselinovic

et al. 2010

Carbohydrate Polymers

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“…Generally, polysaccharides are produced by both lichen symbionts. The mycobiont cell wall contains three structurally different polysaccharides, namely, β‐glucans, α‐glucans, and galactomannans (Olafsdottir and Ingolfsdottir, ; Carbonero et al, ). The β‐glucans, α‐glucans, and galactomannans have linear, lightly substituted, and branched structure (Carbonero et al, ).…”

Section: Lichen Polysaccharidesmentioning

confidence: 99%

The Immunostimulating Role of Lichen Polysaccharides: A Review

2014

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The immune system has capacity to suppress the development or progression of various malignancies including cancer. Research on the immunomodulating properties of polysaccharides obtained from plants, microorganisms, marine organisms, and fungi is growing rapidly. Among the various potential sources, lichens, symbiotic systems involving a fungus and an alga and/or a cyanobacterium, show promise as a potential source of immunomodulating compounds. It is well known that lichens produce an abundance of structurally diverse polysaccharides. However, only a limited number of studies have explored the immunostimulating properties of lichen polysaccharides. Published studies have shown that some lichen polysaccharides enhance production of nitrous oxide (NO) by macrophages and also alter the production levels of various proinflammatory and antiinflammatory cytokines (IL-10, IL-12, IL-1β, TNF-α, and IFN-α/β) by macrophages and dendritic cells. Although there are only a limited number of studies examining the role of lichen polysaccharides, all results suggest that lichen polysaccharides can induce immunomodulatory responses in macrophages and dendritic cells. Thus, a detailed evaluation of immunomodulatory capacity of lichen polysaccharides could provide a unique opportunity for the discovery of novel therapeutic agents.

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“…Three different polysaccharide structural types: -glucans, -glucans (linear or lightly substituted), and galactomannans (branched) (Carbonero et al, 2005a) are present in the fungal cell wall. According to Olafsdottir and Ingólfsdóttir (2001), all the polymers present in lichen thalli are categorized into glucan type [ -(1→3)(1→4)], lichenan type [ -(1→3)(1→4)] and pustulan [ -(1→6)].…”

Section: Biological Source Of the Polysaccharide Fractionmentioning

confidence: 99%

“…Some of these types are depicted in Table 1. However, the recent discovery of a few additional complex heteroglycans, such as rhamnogalactofuranan (Olafsdottir, 1999), galactomannoglucans (Woranovicz-Barreira, 1999 andCarbonero et al, 2002) and thamnolan (Carbonero et al, 2005a) necessitated the closer examination of the origins of the polysaccharides. Studies carried out by Cordeiro et al, (2005), revealed that the algal partner (Trebouxia sp.)…”

Section: Biological Source Of the Polysaccharide Fractionmentioning

confidence: 99%