Gait speed has comparable prognostic capability to six-minute walk distance in older patients with cardiovascular disease

Kamiya, Kentaro; Hamazaki, Nobuaki; Matsue, Yuya; Mezzani, Alessandro; Corrà, Ugo; Matsuzawa, Ryota; Nozaki, Kohei; Tanaka, Shinya; Maekawa, Emi; Noda, Chiharu; Yamaoka‐Tojo, Minako; Matsunaga, Atsuhiko; Masuda, Takashi; Ako, Junya

doi:10.1177/2047487317735715

Cited by 103 publications

(71 citation statements)

References 38 publications

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“…[31][32][33] The prevalence rates of weakness and slowness among elderly participants vary depending on the population and the definitions used [34]. In the NILS-LSA study, a population-based survey of aging, the prevalence rates of weakness and slowness defined according to the AWGS criteria were 15.7% and 7.3%, respectively (10.0% and 5.4% in men, and 15.7% and 9.1% in women) [35].…”

Section: Discussionmentioning

confidence: 99%

Sarcopenia: Prevalence and Prognostic Implications in Elderly Patients with Cardiovascular Disease

Kamiya

Hamazaki²,

Matsuzawa³

et al. 2017

JCSM Clinical Reports

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Aims Sarcopenia has recently been given an ICD-10 code. However, there have been no systematic investigations regarding the prevalence or prognostic value of sarcopenia in cardiovascular disease (CVD) according to the international consensus definition. The present study was performed to investigate the prevalence and prognostic value of sarcopenia in elderly patients with CVD. Methods and resultsThe study population consisted of 1603 admitted patients aged ≥ 65 years (74.4 ± 6.2 years, 1049 men) with CVD. Sarcopenia was defined according to the recommended diagnostic algorithm of the Asia Working Group for Sarcopenia. The endpoint for the study was all-cause mortality. The overall sarcopenia prevalence rate was 29.7% (19.6% in men and 48.7% in women). The prevalence rates of sarcopenia across major diagnostic categories were as follows: acute coronary syndrome, 17.8%; post-cardiac surgery, 31.8%; and heart failure, 35.2%. During the 2.3 ± 2.1-year follow-up period, 175 deaths occurred. Patients with sarcopenia showed higher risk of allcause mortality compared with non-sarcopenic patients (adjusted hazard ratio: 1.44; 95% confidence interval: 1.01 -2.05; P = 0.044).Conclusions Sarcopenia is highly prevalent among elderly patients with CVD and is associated with increased mortality risk.

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Section: Discussionmentioning

confidence: 99%

Sarcopenia: Prevalence and Prognostic Implications in Elderly Patients with Cardiovascular Disease

Kamiya

Hamazaki²,

Matsuzawa³

et al. 2017

JCSM Clinical Reports

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“…29 There is a relation between low gait speed and increased mortality in elderly patients undergoing cardiac surgery. 30,31 In a study by Kamiya and colleagues gait speed was comparable to the 6MWT in a subgroup of patients undergoing cardiac surgery. 31 No studies have compared gait speed with 6MWT with regard to myocardial injury and mortality in patients undergoing non-cardiac surgery.…”

Section: The Literaturementioning

confidence: 96%

Added value of subjective assessed functional capacity before non-cardiac surgery in predicting postoperative myocardial injury

Marsman

Waes

Grobben

et al. 2020

European Journal of Preventive Cardiology

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Background Functional capacity is used as an indicator for cardiac testing before non-cardiac surgery and is often performed subjectively. However, the value of subjectively estimated functional capacity in predicting cardiac complications is under debate. We determined the predictive value of subjectively assessed functional capacity on postoperative cardiac complications and mortality. Design An observational cohort study in patients aged 60 years and over undergoing elective inpatient non-cardiac surgery in a tertiary referral hospital. Methods Subjective functional capacity was determined by anaesthesiologists. The primary outcome was postoperative myocardial injury. Secondary outcomes were postoperative inhospital myocardial infarction and one year mortality. Logistic regression analysis and area under the receiver operating curves were used to determine the added value of functional capacity. Results A total of 4879 patients was included; 824 (17%) patients had a poor subjective functional capacity. Postoperative myocardial injury occurred in 718 patients (15%). Poor functional capacity was associated with myocardial injury (relative risk (RR) 1.7, 95% confidence interval (CI) 1.5–2.0; P < 0.001), postoperative myocardial infarction (RR 2.9, 95% CI 1.9–4.2; P < 0.001) and one year mortality (RR 1.7, 95% CI 1.4–2.0; P < 0.001). After adjustment for other predictors, functional capacity was still a significant predictor for myocardial injury (odds ratio (OR) 1.3, 95% CI 1.0–1.7; P = 0.023), postoperative myocardial infarction (OR 2.0, 95% CI 1.3–3.0; P = 0.002) and one year mortality (OR 1.4, 95% CI 1.1–1.8; P = 0.003), but had no added value on top of other predictors. Conclusions Subjectively assessed functional capacity is a predictor of postoperative myocardial injury and death, but had no added value on top of other preoperative predictors.

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“…Currently, various methods are used to assess physical frailty, but due to its simplicity and predictive capability, gait speed has become a core strategy to evaluate physical frailty. Gait speed has been shown to predict morbidity and mortality in various populations [24,25]. In addition, the evaluation of gait speed is reliable and accurately measures even frail older adults with cognitive dysfunction, which is common comorbidity in the elderly population [26].…”

Section: Discussionmentioning

confidence: 99%

The maximal gait speed is a simple and useful prognostic indicator for functional recovery after total hip arthroplasty

Shibuya

Nanri

Kamiya

et al. 2020

BMC Musculoskelet Disord

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Purpose: The present study aimed to compare the capabilities of preoperative usual and maximal gait speeds in predicting functional recovery in patients who have undergone total hip arthroplasty (THA). Methods: Primary and unilateral THAs were performed in 317 patients, and the proportion of patients who achieved unassisted walking (functional recovery) 5 days postoperatively was recorded as an outcome measure. Preoperative functional assessment included hip pain, leg muscle strength, range of motion (ROM), and gait speed evaluations. The capabilities of preoperative usual and maximal gait speeds in predicting functional recovery were compared based on the areas under the curves (AUCs) of receiver operating characteristic (ROC) curves. Further, ROC curves were constructed using two models: 1. a model of gait speed only and 2. a clinical model including age, sex, leg muscle strength, and ROM. Results: On the AUCs for predictive ability of functional recovery, maximal gait speed was greater than usual gait speed (0.66 and 0.70, respectively). The AUC for maximal gait speed was as large as that of the clinical model (0.70 and 0.70, respectively). Conclusion: Our results suggest that maximal gait speed is a simple and useful prognostic indicator of functional recovery in patients who have undergone THA.

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Gait speed has comparable prognostic capability to six-minute walk distance in older patients with cardiovascular disease

Cited by 103 publications

References 38 publications

Sarcopenia: Prevalence and Prognostic Implications in Elderly Patients with Cardiovascular Disease

Sarcopenia: Prevalence and Prognostic Implications in Elderly Patients with Cardiovascular Disease

Added value of subjective assessed functional capacity before non-cardiac surgery in predicting postoperative myocardial injury

The maximal gait speed is a simple and useful prognostic indicator for functional recovery after total hip arthroplasty

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