2020
DOI: 10.1016/j.lfs.2020.118058
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Gaining insights on immune responses to the novel coronavirus, COVID-19 and therapeutic challenges

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Cited by 12 publications
(11 citation statements)
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“…This technique revealed normal frequencies of total leukocytes, lymphocytes and neutrophil blood counts in PE patients at admission ( Table 1 ). However, among the T cells, the frequencies of CD8 + T cells, important effectors of early antiviral immunity [ 7 ], were increased, whereas regulatory T cells (Tregs), which control immune responses including CD8 + T cells [ [8] , [9] , [10] ], and monocytes, which have been reported to accumulate at sites of Covid-19 infection and simultaneously disappear from the circulation [ 11 ], were less frequent in PE patients ( Fig. 2 ).…”
Section: Resultsmentioning
confidence: 99%
“…This technique revealed normal frequencies of total leukocytes, lymphocytes and neutrophil blood counts in PE patients at admission ( Table 1 ). However, among the T cells, the frequencies of CD8 + T cells, important effectors of early antiviral immunity [ 7 ], were increased, whereas regulatory T cells (Tregs), which control immune responses including CD8 + T cells [ [8] , [9] , [10] ], and monocytes, which have been reported to accumulate at sites of Covid-19 infection and simultaneously disappear from the circulation [ 11 ], were less frequent in PE patients ( Fig. 2 ).…”
Section: Resultsmentioning
confidence: 99%
“…Lymphocyte counts seem to be directly correlated with disease severity and mortality. The reason for lymphopenia might partially be attributed to the injured lymphatic organs expressing ACE2 receptors (Hajivalili et al, 2020;Lega et al, 2020).…”
Section: Immune Cellsmentioning
confidence: 99%
“…The coronavirus disease rapidly spread to other areas in China and other countries (Hajivalili et al, 2020;World Health Organization, 2020) since its outbreak in Wuhan, China. The COVID-19 has triggered a global health crisis and is a major public health emergency of international concern (PHEIC) all over the world, which not only threatens the lives of people but also affects their mental health (World Health Organization, 2005Zhong et al, 2021).…”
Section: Introductionmentioning
confidence: 99%
“…The current research has shown that during the pandemic, the mental health of college students has been affected to some extent, and the number of students with negative emotions and psychological problems has increased (Khan et al, 2020), revealing the possible mental health impact of COVID-19 on them. Hence, we hypothesized that (Hajivalili et al, 2020) COVID-19 would have adverse effects on the mental health of college students (World Health Organization, 2020). The prevalence of these mental health issues would be affected by nations, gender, and the survey date, etc.…”
Section: Introductionmentioning
confidence: 99%