Gadoxetic acid‐enhanced fat suppressed three‐dimensional T1‐weighted MRI using a multiecho dixon technique at 3 tesla: Emphasis on image quality and hepatocellular carcinoma detection

Abstract

For gadoxetic acid-enhanced liver MRI, mDixon-eTHRIVE showed improved homogeneity of fat suppression and overall image quality compared with SPAIR-eTHRIVE.

The Dixon technique and the frequency-selective fat suppression technique in three-dimensionalT1weighted MRI of the liver: a comparison of contrast-to-noise ratios of hepatocellular carcinomas-to-liver

“…9 We believe our quantitative approach has a higher degree of objectivity than that of a receiver operating characteristic analysis. Other strengths of our study are the large number of patients included and that the compared images were obtained at an interval of less than 1 min, as opposed to several months in another study.…”

“…Other strengths of our study are the large number of patients included and that the compared images were obtained at an interval of less than 1 min, as opposed to several months in another study. 9 The CNR is composed of two factors, namely the contrast and signal-to-noise ratio (SNR). Our results show that the CNR derived from mDixon was higher than that derived from e-Thrive, whereas there were no significant differences in contrast measurements.…”

“…mDixon has demonstrated superior image quality and improved FS compared with conventional FS techniques in Gd-enhanced 3D T 1 weighted MRI at 1.5 T. 7,8 In another study, Gd-enhanced 3D T 1 weighted gradient echo images at 3.0 T using mDixon showed superior homogeneity of FS and overall image quality compared with those using e-Thrive. 9 To date, there are a limited number of objective comparisons of image quality between mDixon and e-Thrive, particularly within the same patient and examination. 9 Although a visual assessment of mDixon and e-Thrive has been reported, 9 little has been reported on quantitative analysis.…”

“…9 To date, there are a limited number of objective comparisons of image quality between mDixon and e-Thrive, particularly within the same patient and examination. 9 Although a visual assessment of mDixon and e-Thrive has been reported, 9 little has been reported on quantitative analysis.…”

Focal Liver Lesions

“…T1-weighted MRI can be now performed using a 3D DIXON technique, which can generate in-phase, out-of-phase, water-only, and fat-only images of the whole liver volume in a single breath-hold acquisition. The resultant water-only images have been shown to improve the uniformity of fat suppression at 3 T, compared with conventional spectral fat suppression technique [16]. The use of the DIXON images for dynamic contrast-enhanced acquisition has also been shown to improve the detection of hepatocellular carcinoma compared with standard fat-suppressed sequences.…”