GABAergic Cell Types in the Lizard Hippocampus

Guirado, Salvador; Jc, Dávila

doi:10.1076/ejom.37.2.89.4742

Cited by 6 publications

(3 citation statements)

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“…In amniotes, cortical subpopulations of neurons are distinctly labeled for CB and CR, making the study of the distribution of these calcium binding proteins of special significance for establishing cell types and cortical subdivisions (Dávila et al, ; DeFelipe, ; Chiry, Tardif, Magistretti, & Clarke, ; Krutzfeldt & Wild, ; Suárez, Dávila, Real, & Guirado, ; Suárez, Dávila, Real, Guirado, & Medina, ). In general, different types of nonpyramidal neurons are stained for each protein and display different neurochemical characteristics (Martínez‐Guijarro & Freund, ; DeFelipe, ; Guirado & Dávila, ; Wild, Williams, Howie, & Mooney, ; Suárez et al, ; Rahman & Baizer, ).…”

Section: Discussionmentioning

confidence: 99%

Regional chemoarchitecture of the brain of lungfishes based on calbindin D‐28K and calretinin immunohistochemistry

Morona

López

Northcutt

et al. 2018

J of Comparative Neurology

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Lungfishes are the closest living relatives of land vertebrates, and their neuroanatomical organization is particularly relevant for deducing the neural traits that have been conserved, modified, or lost with the transition from fishes to land vertebrates. The immunohistochemical localization of calbindin (CB) and calretinin (CR) provides a powerful method for discerning segregated neuronal populations, fiber tracts, and neuropils and is here applied to the brains of Neoceratodus and Protopterus, representing the two extant orders of lungfishes. The results showed abundant cells containing these proteins in pallial and subpallial telencephalic regions, with particular distinct distribution in the basal ganglia, amygdaloid complex, and septum. Similarly, the distribution of CB and CR containing cells supports the division of the hypothalamus of lungfishes into neuromeric regions, as in tetrapods. The dense concentrations of CB and CR positive cells and fibers highlight the extent of the thalamus. As in other vertebrates, the optic tectum is characterized by numerous CB positive cells and fibers and smaller numbers of CR cells. The so-called cerebellar nucleus contains abundant CB and CR cells with long ascending axons, which raises the possibility that it could be homologized to the secondary gustatory nucleus of other vertebrates. The corpus of the cerebellum is devoid of CB and CR and cells positive for both proteins are found in the cerebellar auricles and the octavolateralis nuclei. Comparison with other vertebrates reveals that lungfishes share most of their features of calcium binding protein distribution with amphibians, particularly with salamanders.

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Section: Discussionmentioning

confidence: 99%

Regional chemoarchitecture of the brain of lungfishes based on calbindin D‐28K and calretinin immunohistochemistry

Morona

López

Northcutt

et al. 2018

J of Comparative Neurology

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“…In general, different types of nonpiramidal neurons are stained for each protein and display different neurochemical characteristics [Martínez-Guijarro and Freund, 1992;DeFelipe, 1997;Guirado and Dávila, 1999;Wild et al, 2005;Suárez et al, 2006;Rahman and Baizer, 2007]. Strikingly different to amniotes are the results described for nonamphibian anamniotes in which CBP-containing cells are absent or very scarce in pallial regions [Díaz-Regueira and Anadón, 2000].…”

Section: Palliummentioning

confidence: 97%

Localization of Calbindin-D28k and Calretinin in the Brain of Dermophis Mexicanus (Amphibia: Gymnophiona) and Its Bearing on the Interpretation of Newly Recognized Neuroanatomical Regions

Morona¹,

López²,

González³

2011

Brain Behav Evol

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The analysis of the distribution of the calbindin-D28k and calretinin immunoreactive (CBir and CRir) systems recently described in the brain of anuran and urodele amphibians was very useful for the interpretation of many otherwise indistinct brain regions and cell masses. In the present study we have followed a similar approach to investigate the distribution of CBir and CRir cell bodies and fibers in the brain of Dermophis mexicanus, a member of the much neglected third amphibian order of gymnophionans. The pattern of distribution obtained showed particular characteristics in Dermophis, such as the existence of abundant CRir elements in the olfactory bulbs and CBir and CRir cell populations in pallial areas. The distinct distribution of the two proteins allowed the tentative identification of currently described subregions, mainly in the amygdaloid complex and hypothalamic areas. The analysis of the diencephalon and brainstem distribution framed in the neuromeric model highlighted common traits with other amphibians but also specific features. Therefore, the immunohistochemical detection of calcium-binding proteins has served to discern cell populations and has helped to demonstrate neuronal heterogeneity. However, it should be pointed out that a straightforward comparison based only on the presence of these proteins should not be made due to the great variability observed in well-established homologous regions in the brain of different vertebrates, as evidenced within the class Amphibia.

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“…For studies on cortical volume changes in relation to spatial navigation [Day et al, 1999;Ladage et al, 2009] we direct the reader to excellent reviews that also incorporate a broader phylogenetic perspective [Roth et al, 2010;Broglio et al, 2015;Murray et al, 2016;Striedter, 2016;Bingman et al, 2017]. Similarly, we omit studies on cortical interneurons in reptiles [reviewed in Reiner, 1991;Guirado and Davila, 1999;Naumann and Laurent, 2017], since, despite extensive knowledge about cell type diversity of mammalian hippocampal interneurons, their function remains poorly understood [Grieves and Jeffery, 2017].…”

Section: The Hippocampus In Pieces and Patchesmentioning

confidence: 99%

On the Value of Reptilian Brains to Map the Evolution of the Hippocampal Formation

Reiter

Liaw²,

Yamawaki³

et al. 2017

Brain Behav Evol

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Our ability to navigate through the world depends on the function of the hippocampus. This old cortical structure plays a critical role in spatial navigation in mammals and in a variety of processes, including declarative and episodic memory and social behavior. Intense research has revealed much about hippocampal anatomy, physiology, and computation; yet, even intensely studied phenomena such as the shaping of place cell activity or the function of hippocampal firing patterns during sleep remain incompletely understood. Interestingly, while the hippocampus may be a ‘higher order' area linked to a complex cortical hierarchy in mammals, it is an old cortical structure in evolutionary terms. The reptilian cortex, structurally much simpler than the mammalian cortex and hippocampus, therefore presents a good alternative model for exploring hippocampal function. Here, we trace common patterns in the evolution of the hippocampus of reptiles and mammals and ask which parts can be profitably compared to understand functional principles. In addition, we describe a selection of the highly diverse repertoire of reptilian behaviors to illustrate the value of a comparative approach towards understanding hippocampal function.

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GABAergic Cell Types in the Lizard Hippocampus

Cited by 6 publications

References 0 publications

Regional chemoarchitecture of the brain of lungfishes based on calbindin D‐28K and calretinin immunohistochemistry

Regional chemoarchitecture of the brain of lungfishes based on calbindin D‐28K and calretinin immunohistochemistry

Localization of Calbindin-D28k and Calretinin in the Brain of Dermophis Mexicanus (Amphibia: Gymnophiona) and Its Bearing on the Interpretation of Newly Recognized Neuroanatomical Regions

On the Value of Reptilian Brains to Map the Evolution of the Hippocampal Formation

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