G51 Admissions to PICU in England and Wales with Refractory Convulsive Status Epilepticus: A Two-Year National Epidemiological Study

Abstract

g50 figure 1 Number of ex-premature babies admitted to PICU in the first 2 years of life by gestation. Conclusions Approximately one third of the patients admitted to PICU with RCSE had been treated in the ED appropriately using the APLS algorithm. Thiopentone was the most commonly used first-choice anticonvulsant to treat RCSE on admission to PICU. Mortality was low and approximately 1 in 25 showed a new neurological deficit at the 30-day follow-up. In ED the APLS guidelines were followed precisely in 90 patients (36.7%); 88 patients (35.9%) received an inappropriate dose of benzodiazepine (above guideline dose in 62, below guideline dose in 26). Thirty seven patients (15.1%) received anticonvulsants in the wrong sequence.The mean duration of admission to PICU was 3.7 days (range 1-45, median 2). The mean length of days ventilated (on PICU) was 3.2 days ventilated (range 1-31, median 2).Nine patients died (3.7%). Twenty seven patients (11%) demonstrated a new neurological deficit on discharge from PICU, of whom 10 (4% of the entire cohort) continued to show this deficit at 30 days. Abstract g50 figure 2Percentage of ex-premature babies alive at day 28 of life who are admitted to PICU before their second birthday by gestation. Abstract g50 figure 3Length of stay by gestation, median and IQR.