G-Quadruplexes in the Regulation of Viral Gene Expressions and Their Impacts on Controlling Infection
Andrew R. Zareie,
Prerna Dabral,
Subhash C. Verma
Abstract:G-quadruplexes (G4s) are noncanonical nucleic acid structures that play significant roles in regulating various biological processes, including replication, transcription, translation, and recombination. Recent studies have identified G4s in the genomes of several viruses, such as herpes viruses, hepatitis viruses, and human coronaviruses. These structures are implicated in regulating viral transcription, replication, and virion production, influencing viral infectivity and pathogenesis. G4-stabilizing ligands… Show more
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