G protein-coupled receptors and traditional Chinese medicine: new thinks for the development of traditional Chinese medicine
Ting Zhang,
Wenqiao An,
Shengjie You
et al.
Abstract:G protein-coupled receptors (GPCRs) widely exist in vivo and participate in many physiological processes, thus emerging as important targets for drug development. Approximately 30% of the Food and Drug Administration (FDA)-approved drugs target GPCRs. To date, the ‘one disease, one target, one molecule’ strategy no longer meets the demands of drug development. Meanwhile, small-molecule drugs account for 60% of FDA-approved drugs. Traditional Chinese medicine (TCM) has garnered widespread attention for its uniq… Show more
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