Fxofenadine: Prophylactic Treatment in Allergic Rhinitis

Abstract

Allergic rhinitis is commonly found in Kashmir. Prophylactic Fexofenadine shows more promising activity with mild side effects at proper dosage schedule. 10 cases of Allergic Rhinitis were studied during a period from Jan 2013 to July 2015.Clinical symptomatology of Allergic rhinitis are described as recurrent ,episodic profuse mucoid nasal discharge, excessive sneezing and nasal obstruction. The associated symptoms being itching and burning sensation of conjunctiva, nasal mucosa and Oropharynx and the aggravation of the symptoms coincident with the pollination. The prophylactic treatment with Fexofenadine 120 mg once daily for 3 weeks with 1 week drug wash-out interval in a month has proven very effective in preventing the acute attack of allergic rhinitis. The drug has been tried for such a prolonged time and is virtually free of side effects and toxicity (clinically) on such dosage.