Future Plans Of Treating A Case Of Acquired Pure Red Cell Aplasia Secondary To Autoimmune Causes Resistant To Combination Of Cyclosporine And Corticosteroid

Abstract

Background and objectives: IgE-mediated egg allergy is commonly found in the paediatric population. Traditionally, management of egg allergy was through egg avoidance. The Irish College of General Practitioners and other paediatric societies across the globe recommend reintroducing egg into the diet to improve tolerance and quality of life. Oral immunotherapy (OIT) has been emerging as a potential method to induce desensitisation and even long-term tolerance in children with egg allergy, with many trials reporting significant differences after its implementation. The aim of this study is to combine and appraise the literature on OIT methods that have been trialed to improve tolerance in paediatric populations with IgE egg allergy and their outcomes. Methodology: A search strategy based on the objectives of this review was used to conduct electronic searches on PubMed and Wiley Online Library. After the application of filters, 152 articles were obtained and after application of the inclusion and exclusion criteria, ten articles satisfying the criteria of this review were identified.