Future perspectives of digital pathology

Abstract

Technological advances have enabled innovative solutions to be achieved in pathology based on digital imaging, now superseding those of conventional microscopy. Digital pathology has been defined as 'virtual microscopy' and depends on computer-generated digital imaging of microscope slides (WSI -whole slide imaging) which are in turn created, reviewed, managed, shared, analysed and interpreted. Such WSI systems and digital consulting platforms are now used for teaching, scientific research, telepathology / teleconsultation and diagnostics. They also permit easy and interactive sharing of WSI that can be integrated into other medical information systems. The software for automated image analysis and computer aided diagnosis can thereby make highly accurate diagnoses and help standardise study findings. Despite the technique's many advantages, its noted drawbacks include high equipment and software costs, image quality issues of standardisation and most importantly, that pathologists are reluctant to use it routinely for making diagnoses. NOWOTWORY J Oncol 2016; 66, 4: 277-285

Sustained Response to Ruxolitinib of Eosinophilia-Associated Myeloproliferative Neoplasm with Translocation t(8;9)(p21;p24)

“…We summarize cases reported with t(8;9)/ PCM1-JAK2 in online suppl. Table . At least 42 cases have been previously reported to have this abnormality [1][2][3][4][5][6][7][8][9][10][13][14][15][16][17][18][19][20]. The break points of the 2 genes are various, involving exon 23 to exon 36 of PCM1 and exon 1 to exon 11 of JAK2.…”

Applications of Artificial Intelligence (AI) in medicine

“…Działanie w jej zakresie polega na wykonywaniu serii zdjęć preparatów mikroskopowych za pomocą skanera, dzięki czemu generowane są wysokiej rozdzielczości zdjęcia całego preparatu (z ang. whole slide imaging -WSI lub virtual microscopy) [40][41][42]. Obrazy te mogą zostać przesłane za pomocą Internetu do patomorfologów na całym świecie, np.…”

“…w celu konsultacji lub prowadzenia badań naukowych. Również sam algorytm zdolny jest do analizy WSI [40,41].…”