Future Perspectives in the Management of Otitis Media

Frosolini, Andrea; Lovato, Andrea

doi:10.3390/medicina59091553

Cited by 1 publication

(2 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…После установки ТСТ изучалось бактериологическое исследование полученного отделяемого из барабанной полости. Терапия пациентов проходила согласно действующим стандартам по лечению хронического секреторного среднего отита 1 Так, пациентам назначалась системная антибактериальная терапия с учетом результатов посева на питательные среды, противовоспалительная и муколитическая терапия, физиолечение. Местная эндоназальная терапия для улучшения функции слуховой трубы.…”

Section: ) наличие у пациента системных аутоиммунных и иммуносупресси...unclassified

“…Результатом вялотекущего воспалительного процесса в полости среднего уха являются различные формы хронического среднего отита, которые при недостаточно подобранном лечении не способны разрешиться в течение длительного времени [1,2]. Поскольку момент перехода воспаления в хроническую форму индивидуален для каждого пациента и не всегда уловим для лечащего врача, следует принимать во внимание не только причины, вызывающие острое воспаление в среднем ухе, но и факторы, пролонгирующие течение заболевания, тем самым ведущие к переходу в его следующую фазу.…”

Section: Introductionunclassified

See 1 more Smart Citation

The GERD-caused middle ear mucous membrane transformation features in chronic otitis media with effusion

Komarov,

Fedotova,

Bezrukova

et al. 2024

Medicinskij sovet

View full text Add to dashboard Cite

Introduction. Chronic otitis media with effusion (COME) is a middle ear disease, characterized by mucous effusion accumulation in its structures. One of the important COME formation mechanism is gastric reflux. Gastric contents reflux into the tympanic cavity which contributes to the irreversible transformation of its mucous membrane.Aim. To substantiate the significance of the gastric reflux in the middle ear mucosa fibrous remodeling.Materials and methods. The study included 96 people diagnosed with COME and concomitant gastroesophageal reflux disease (GERD), 54 women and 42 men, in the age range from 18 to 65 years (mean age 51.4 years). All patients underwent tympanostomy tube installation and supervised by an otolaryngologist during 12 months. Patients were divided into 2 groups depending on their consent to GERD therapy. The conservative treatment of COME and GERD was carried out in accordance with established and current medical care standards and clinical guidelines for the relevant nosology.Results and discussion. 14 days after the tympanostomy, the otorrhea decrease was noted in 31 (75.6%) of the main group and 31 (56.6%) participants in the comparison group (n = 96).By the end of 12 months observation a positive disease outcome such as exudation reduction and complete tympanic membrane repair was recorded in 35 (83.3%) and 25 (62.5%) patients of both groups respectively (n = 82).Patients with a mixed 34 (35.4%) and non-acid 11 (11.5%) types of reflux showed worse disease outcome rates, just like in patients with COME who delayed GERD treatment 8 (8.3%).Conclusions. The combination of infectious agent exposure causes an active mucous membrane exudation in the disease early stages with mixed and non-acid gastric reflux leads to mucous membrane middle ear fibrous remodeling. It has also been established that an unsuccessful COME treatment duration aggravates the outcome of the disease in the absence of GERD therapy.

show abstract

Section: ) наличие у пациента системных аутоиммунных и иммуносупресси...unclassified

Section: Introductionunclassified

The GERD-caused middle ear mucous membrane transformation features in chronic otitis media with effusion

Komarov,

Fedotova,

Bezrukova

et al. 2024

Medicinskij sovet

View full text Add to dashboard Cite

show abstract

Future Perspectives in the Management of Otitis Media

Abstract: Otitis media, which encompasses acute otitis media (AOM) and chronic otitis media (COM), is a prevalent and significant health issue affecting both children and adults [...]

Cited by 1 publication

References 15 publications

The GERD-caused middle ear mucous membrane transformation features in chronic otitis media with effusion

The GERD-caused middle ear mucous membrane transformation features in chronic otitis media with effusion

Contact Info

Product

Resources

About