Future of transcatheter aortic valve implantation: where do we go from here?

Left ventricular ejection fraction: clinical, pathophysiological, and technical limitations

“…Only surgical or transcatheter aortic valve replacement (TAVR) can prevent disease progression and poor clinical outcomes ( 100 ). Currently, expanding indications of early TAVR in asymptomatic, younger, and low-risk patients are being evaluated ( 101 ).…”

Heartbeat: clinical practice patterns for valve intervention in adults with aortic stenosis

“…The Education in Heart article4 in this issue provides further discussion on the future of TAVI including emerging indications; procedural changes; management post TAVI; complications such as stroke, permanent pacing, limited coronary access and valve thrombosis; as well as the issue of long-term valve durability (figure 2).…”

Optimizing Age-Specific Outcomes After Mechanical vs Bioprosthetic Prosthetic Heart Valve Replacement

“…Even if there might be a higher risk of permanent pacer implantation with the transcatheter approach, patients often consider that avoidance of a chest wall scar and cardiopulmonary bypass, with a shorter hospitalization, less pain, and more rapid return to normal activities, outweighs any disadvantages of a bioprosthetic valve. 6 Looking forward, it is likely that the optimal age thresholds for a specific valve type will shift with advances in valve disease therapies. Ideally, medical therapies will be developed to prevent, slow, or reverse valve disease progression.…”

“…In patients considering AVR, the options of a transcatheter intervention rather than a surgical procedure also impacts clinical decision-making. Even if there might be a higher risk of permanent pacer implantation with the transcatheter approach, patients often consider that avoidance of a chest wall scar and cardiopulmonary bypass, with a shorter hospitalization, less pain, and more rapid return to normal activities, outweighs any disadvantages of a bioprosthetic valve …”