Future directions for conservative treatment of gallbladder calculi

Abstract

Recent conservative gallstone treatments provide rapid relief from symptoms, but all have a potential for stone recurrence. They are indicated in patients who are unfit or unwilling to undergo cholecystectomy. Wider application will depend on selection of patients who are at least risk of recurrence, or on development of effective prophylactic strategies.

Targets for Current Pharmacologic Therapy in Cholesterol Gallstone Disease

“…Oral dissolution therapy of cholesterol gallstones with bile acids might still represent the option in patients who are at minimal risk of gallstone recurrence or have transient risk factors including rapid weight loss (i.e. obese patients following bariatric surgery), pregnancy, and convalescence from abdominal surgery, (1;119-121)). Major limitations for oral litholysis with bile acids, by contrast, are the small number of suitable patients and the high rate of gallstone recurrence (37;122;123).…”

Cholelithiasis and Ayurveda

“…Thyroid hypo function not only alter the Calcium metabolism but also cause bile concentration leading to Cholelithiasis, as a dictum female, fatty and fourty most commonly prone for cholelithiasis 3,4,5 and present with eructation, heart burn, indigestion, heaviness and pain in the abdomen. In addition changed diaetary and life style also alter the normal digestion and metabolic process due to non nutrient toxic constituent of the food and drinks.. 6,7,8,9 The bile super saturation with cholesterol is a key factor of cholelithiasis.…”

Cholelithiasis and Ayurveda

“…Thyroid hypo function not only alter the Calcium metabolism but also cause bile concentration leading to Cholelithiasis, as a dictum female, fatty and fourty most commonly prone for cholelithiasis [3][4][5] and present with eructation, heart burn, indigestion, heaviness and pain in the abdomen. In addition changed diaetary and life style also alter the normal digestion and metabolic process due to non nutrient toxic constituent of the food and drinks [6][7][8][9].…”