Fusion Status and Clinical Outcomes at One Year and Two Years of Instrumented, Local Bone Transforaminal Lumbar Interbody Fusion

Kawaguchi, Satoshi; Oguma, Hiroshi; Yamamura, Megumu; Akatsuka, Tomohiro; Matsuo, Shingo; Ono, Nobuhide; Horigome, Keiko; Yajima, Hideki; Oda, Takashi; Yamazaki, Ikuo

doi:10.4172/2165-7939.1000103

Cited by 1 publication

(1 citation statement)

References 22 publications

(36 reference statements)

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“…These patients were divided into 2 separate cohorts—according to time after surgery—6 and 12 months. A period of 6 months was chosen as this is a common short-term follow-up period used in comparable TLIF studies 2 , 12 ; 12 months was chosen because it is widely accepted as the cutoff when patients can be considered to have achieved fusion or not. Indications for surgery included diagnoses of spondylolisthesis, recurrent herniated disc, degenerative disc disease, or spinal stenosis.…”

Section: Clinical Materials and Methodsmentioning

confidence: 99%

Transforaminal lumbar interbody fusion rates in patients using a novel titanium implant and demineralized cancellous allograft bone sponge

Girasole¹,

Muro²,

Mintz³

et al. 2013

The International Journal of Spine Surgery

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Background Transforaminal lumbar interbody fusion (TLIF) with grafting and implant options like iliac crest bone graft (ICBG), recombinant bone morphogenetic protein (rhBMP), and polyetheretherketone (PEEK) cages have been reported to achieve extremely high fusion rates. Unfortunately, these options have also been frequently cited in the literature as causing postoperative morbidity and complications at a high cost. Knowing this, we sought to investigate TLIF using an acid-etched, roughened titanium cage that upregulates osteogenesis to see if similar fusion rates to those cited for ICBG, rhBMP, and PEEK cages could be safely achieved with minimal morbidity and complications. Materials and methods A radiographic fusion study of 82 patients who underwent TLIF using an acid-etched, roughened titanium cage with demineralized cancellous bone graft was conducted. Fusion was assessed and graded by an independent radiologist using computed tomography scan with sagittal and coronal reconstructions. Results Fusion rates at 6 months were 41 of 44 (93.2%) and at 12 months were 37 of 38 (97.4%). There were no radiographic device-related complications. Conclusions TLIF with an acid-etched, roughened titanium cage filled with a decalcified bone graft achieved similar fusion rates to historical controls using ICBG, rhBMP, and PEEK.

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Section: Clinical Materials and Methodsmentioning

confidence: 99%