Fused pyrazole-phenanthridine based dyads: synthesis, photo-physical and theoretical studies, and live cell pH imaging

Abstract

The arrangement of small sized molecules with a scaffold structure plays an active role in the fields of sensors and health care.

A novel dual-capability naphthalimide-based fluorescent probe for Fe3+ ion detection and lysosomal tracking in living cells

“…At present, there are few Fe 3+ ions uorescent probes that can detect these ions directly, especially when uorescence enhancement (turn-on) response is required. 23 1,8-Naphthalimide and its derivatives play a key role in the uorescent dye eld. They have been extensively applied in biochemistry, polymers, optical storage, uorescent sensors, and biological medicine due to its good thermal and oxidation stability, high electron affinity, large Stokes shis, good photostability, and high uorescence quantum yields.…”

“…At present, there are few Fe 3+ ions fluorescent probes that can detect these ions directly, especially when fluorescence enhancement (turn-on) response is required. 23…”

A Highly Selective and Sensitive Colorimetric Chemosensor for the Detection of Hydrogen Sulfide: A Real‐time Application in Multiple platforms

“…Nevertheless, the research on the development of selective and sensitive chromogenic probes to detect H 2 S is inadequate. As part of our ongoing interest in developing optical sensors for important analytes (71–75), in this work, we developed a simple phenanthridine‐based colorimetric probe to detect H 2 S. In the design of this probe, phenanthridine was incorporated with the 2,4‐dinitrobenzene sulfonyl (DNBS) group, a widely used selective signaling unit for H 2 S. On the other hand, phenanthridine is a simple chromogenic molecule with outstanding advantages of straightforward synthesis, intriguing optical property and easy functionalization. To our surprise, the colorimetric H 2 S sensor derived from DNBS was conspicuously uncommon.…”