Fusariotoxins in Russian Federation 2005–2010 grain harvests

Tutelyan, V A; Lp, Zakharova; Седова, И Б; Perederyaev, O.I.; Aristarkhova, T V; Эллер, К И

doi:10.1080/19393210.2013.767862

Cited by 14 publications

(17 citation statements)

References 6 publications

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“…A Russian group monitored Fusarium toxins in wheat, barley, oats, rye, and maize between 2005 and 2010. Their results demonstrated the presence of T-2 toxin in 14% and HT-2 toxin in 17% of all samples (17). Our results showed that contamination of T-2 and HT-2 in crops also occurred in the pan-Pacific zone, including Japan, Canada, and the United States.…”

Section: Occurrence Of Don Zen T-2 and Ht-2 In Wheatmentioning

confidence: 44%

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Occurrence of Four Fusarium Mycotoxins, Deoxynivalenol, Zearalenone, T-2 Toxin, and HT-2 Toxin, in Wheat, Barley, and Japanese Retail Food

Yoshinari

Takeuchi

Aoyama³

et al. 2014

Journal of Food Protection

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A survey of the contamination of wheat, barley, and Japanese retail food by four Fusarium mycotoxins, deoxynivalenol (DON), zearalenone (ZEN), T-2 toxin (T-2), and HT-2 toxin (HT-2), was performed between 2010 and 2012. A method for the simultaneous determination of the four mycotoxins by liquid chromatography-tandem mass spectrometry was validated by a small-scale interlaboratory study using two spiked wheat samples (DON was spiked at 20 and 100 μg/kg and ZEN, T-2, and HT-2 at 6 and 20 μg/kg in the respective samples). The recovery of the four mycotoxins ranged from 77.3 to 107.2%. A total of 557 samples of 10 different commodities were analyzed over 3 years by this validated method. Both T-2 and HT-2 were detected in wheat, wheat flour, barley, Job's tears products, beer, corn grits, azuki beans, soybeans, and rice with mixed grains. Only T-2 toxin was detected in sesame seeds. The highest concentrations of T-2 toxin (48.4 μg/kg) and HT-2 toxin (85.0 μg/kg) were present in azuki beans and wheat, respectively. DON was frequently detected in wheat, wheat flour, beer, and corn grits. The contamination level of wheat was below the provisional standard in Japan (1,100 μg/kg). The maximum contamination level of DON was present in a sample of a Job's tears product (1,093 μg/kg). ZEN was frequently detected in Job's tears products, corn grits, azuki beans, rice with mixed grains, and sesame seeds. A sample of a Job's tears product presented the highest ZEN contamination (153 μg/kg). These results indicate that continuous monitoring by multiple laboratories is effective and necessary due to the percentage of positive samples detected.

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Section: Occurrence Of Don Zen T-2 and Ht-2 In Wheatmentioning

confidence: 44%

“…The natural occurrence of these mycotoxins is frequent in a wide variety of agricultural products, such as com, wheat, and barley, and is of great concern to animal and human health (11,12,17,18). Trichothecenes can be divided into type A and type B depending on their structures.…”

mentioning

confidence: 99%

Occurrence of Four Fusarium Mycotoxins, Deoxynivalenol, Zearalenone, T-2 Toxin, and HT-2 Toxin, in Wheat, Barley, and Japanese Retail Food

Yoshinari

Takeuchi

Aoyama³

et al. 2014

Journal of Food Protection

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“…In Lithuania, Mankevičienė et al [ 18 ] found that 50% of rye samples were contaminated by DON, with a maximum concentration of 158.9 µg/kg. In one out of 63 rye samples (2%), DON was found at a concentration of 60 µg/kg in a 6-year survey in the Russian Federation [ 19 ]. In another study, Remža et al [ 20 ] analyzed 39 Slovak rye grains, and DON was found at mean and maximum concentrations of 67.9 µg/kg and 289.0 µg/kg, respectively.…”

Section: Resultsmentioning

confidence: 99%

Occurrence of Mycotoxins in Winter Rye Varieties Cultivated in Poland (2017–2019)

Kosicki

Twarużek

Dopierała³

et al. 2020

Toxins

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Rye (Secale cereale L.) is one of the most important cereals and is used in both the food and feed industries. It is produced mainly in a belt extending from Russia through Poland to Germany. Despite the great economic importance of this cereal, there is little research on rye contamination with mycotoxins. In this study, the occurrence of Fusarium mycotoxins (deoxynivalenol, nivalenol, 3-acetyl-deoxynivalenol, monoacetoxyscirpenol, diacetoxyscirpenol, T-2 toxin, HT-2 toxin, and zearalenone), as well as ochratoxin A, in 60 winter rye samples of four varieties (KWS Binntto, KWS Serafino, Dańkowskie Granat and Farm Saved Seed) cultivated in three consecutive growing seasons in five different regions of Poland was determined using liquid chromatography with tandem mass spectrometry and fluorescence detection. Deoxynivalenol, T-2 toxin, HT-2 toxin, and zearalenone had the highest occurrence in samples (90%, 63%, 57%, and 45% positive results, respectively). The mean concentrations of these analytes were 28.8 µg/kg (maximum 354.1 µg/kg), 0.98 µg/kg (maximum 6.63 µg/kg), 2.98 µg/kg (maximum 29.8 µg/kg), and 0.69 µg/kg (maximum 10.2 µg/kg), respectively. The mean concentrations for individual mycotoxins were highest in the 2016/2017 growing season. In the 2016/2017 growing season, at least two mycotoxins were detected in 95% of the samples, while in the 2018/2019 growing season, 70% of samples contained one or no mycotoxins. The frequencies of mycotoxin occurrence in different rye varieties were similar. Although a high frequency of mycotoxin occurrence was noted (especially deoxynivalenol), their concentrations were low, and none of the analyzed rye samples exceeded the maximum acceptable mycotoxin level set by the European Commission.

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“…(Streit et al, ). Although the contamination level of T‐2 toxin is relatively lower than DON worldwide, it is still very common in many areas (Bhat & Reddy, ; EFSA, ; Pascale et al, ; Pinotti et al, ; Tutelyan et al, ; Yoshinari et al, ). T‐2 toxin is also a non‐negligible highly toxic mycotoxin.…”

Section: Introductionmentioning

confidence: 99%

“…In a large‐scale study between 2005 and 2010, T‐2 toxin was present in 23% of the food, feed and unprocessed grains collected from 22 European countries (EFSA, ). The Russian Federation monitoring the presence of Fusarium toxins reported that T‐2 toxin was found in 14% of grain samples harvested in 2005–10 (Tutelyan et al, ). In a Japanese survey between 2010 and 2012, T‐2 toxin was detected in 10% of wheat flour, 20% of corn grits, 22% of Job's tears products, 57% of beers and 70% of adzuki beans (Yoshinari et al, ).…”

Section: Introductionmentioning

confidence: 99%

Individual and combined toxicity of T‐2 toxin and deoxynivalenol on human C‐28/I2 and rat primary chondrocytes

Lin

Shao

et al. 2018

J of Applied Toxicology

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Deoxynivalenol (DON) and T‐2 toxin are prevalent mycotoxin contaminants in the food and feed stuffs worldwide, with non‐negligible co‐contamination and co‐exposure conditions. Meanwhile, they are considerable risk factors for Kashin‐Beck disease, a chronic endemic osteochondropathy. The aim of this study was to investigate the individual and combined cytotoxicity of DON and T‐2 toxin on proliferating human C‐28/I2 and newborn rat primary costal chondrocytes by MTT assay. Four molar concentration combination ratios of DON and T‐2 toxin were used, 1:1 for R1 mixture, 10:1 for R10, 100:1 for R100 and 1000:1 for R1000. The toxicological interactions were quantified by the MixLow method. DON, T‐2 toxin, and their mixtures all showed a clear dose‐dependent toxicity for chondrocytes. The cytotoxicity of T‐2 toxin was 285‐fold higher than DON was in human chondrocytes, and 22‐fold higher in the rat chondrocytes. The combination of DON and T‐2 toxin was significantly synergistic at middle and high level concentrations of R10 mixtures in rat chondrocytes, but significantly antagonistic at the low concentrations of R100 mixtures in both cells and at the middle concentrations of R1000 mixtures in rat chondrocytes. These results indicated that the combined toxicity was influenced by the cell sensitivity for toxins, the difference between the combination ratio and equitoxic ratio, the concentrations and other factors.

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Fusariotoxins in Russian Federation 2005–2010 grain harvests

Cited by 14 publications

References 6 publications

Occurrence of Four Fusarium Mycotoxins, Deoxynivalenol, Zearalenone, T-2 Toxin, and HT-2 Toxin, in Wheat, Barley, and Japanese Retail Food

Occurrence of Four Fusarium Mycotoxins, Deoxynivalenol, Zearalenone, T-2 Toxin, and HT-2 Toxin, in Wheat, Barley, and Japanese Retail Food

Occurrence of Mycotoxins in Winter Rye Varieties Cultivated in Poland (2017–2019)

Individual and combined toxicity of T‐2 toxin and deoxynivalenol on human C‐28/I2 and rat primary chondrocytes

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