Further Observations on the Use of Cetavlon (Ctab) in Surgery

Infection of Burns

“…pyogenes-in the environment by the use, whenever possible, of ample dressings in layers of gauze, cotton-wool, and crepe bandage. This physical barrier was supported by other Williams et al, 1944); (2) the use of a plenum-ventilated dressing-station; (3) the use of local prophylactic chemotherapy (with penicillin cream); and (4) chemotherapy and bed or cubicle isolation for known infections in the ward. The simultaneous application of these methods in Birmingham was associated with a lower incidence (5 %) of streptococcal infection than was found in Glasgow (30%), where prophylactic penicillin cream and plenum ventilation were not used; there was, however, no obvious reduction in the incidence of infection by Staph.…”

Mediastinal Teratoma Removed by Operation

“…He gave 1-g. doses of 2-aminophenol to 6 rabbits of 2.5 kg., apparently without toxic effect. He also showed (Williams, 1943) that 2-and 4-aminophenol glucuronides were methaemoglobin-formers in vitro.…”

“…These workers found that this compound, compared with a large number of similar substances, was the most active in inhibiting the oxygen uptake of liver suspensions. Williams (1938Williams ( , 1943 has studied the fate of 2-, 3-, and 4-aminophenol in the body. He has shown that 2-aminophenol when fed to rabbits by stomach-tube is excreted in conjugation with both sulphuric acid and glucuronic acid.…”

Contamination of Cetrimide and Other Fluids with Pseudomonas pyocyanea

“…Soap solution, cetrimide, " dettol" and calamine lotion are commonly dispensed in large corked or stoppered bottles which are sometimes not replaced for many days, and during that time they are frequently opened. Contamination of such bottles is likely, and the survival or multiplication of some coliforms and especially of Pseudomonas pyocyanea is reported to be possible even in solutions of cetrimide (Williams, Clayton-Cooper, Faulkner, and Thomas, 1944).…”