Further observations on <i>in vitro</i> cytopathic effects associated with murine leukemia virus infection

Tyndall, R. L.; Teeter, E.; Otten, J. A.; Bowles, N. D.; Vidrine, J. G.; Upton, Arthur C.; Walburg, H. E.

doi:10.1002/ijc.2910010605

Cited by 10 publications

(2 citation statements)

References 8 publications

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“…Rauscher leukemia virus grown in vitro (TCRLV) was cultured in a variant, BALB/cderived, JLS V5 cell line (Tyndall et al, 1966) obtained from Dr. Bruce Wright (J. L. Smith Memorial Laboratory, C. Pfizer Co.). TCRLV grown in these cells does not produce an early '' erythroblastic reaction " characteristic of Rauscher disease (Rauscher, 1962;Dunn and Green, 1966).…”

Section: Virusesmentioning

confidence: 99%

The combined action of rauscher leukemia virus and lactic dehydrogenase virus on mouse lymphatic tissue

Proffitt

Congdon

Tyndall

1972

Intl Journal of Cancer

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Section: Virusesmentioning

confidence: 99%

The combined action of rauscher leukemia virus and lactic dehydrogenase virus on mouse lymphatic tissue

Proffitt

Congdon

Tyndall

1972

Intl Journal of Cancer

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“…I t has been suggested( 1) that enteric bacteria play a role in the pathogenesis of chronic ulcerative colitis (UC). I t is known that strains of E. coli which contain capsular (('K'') antigens, particularly of the "B" type, are more pathogenic than non-capsular organisms (2 ). Serum gamma globulins represent one aspect of the defense against Gramnegative bacteria ( 3 ) : we therefore measured the antibody titer against "B" antigens in the sera of patients with UC compared with the titer in patients free of gastrointestinal disease and patients with liver disease.…”

mentioning

confidence: 99%

E. coli Agglutinating Activity of Ulcerative Colitis Sera

Fink

Mais

Locke

et al. 1967

Experimental Biology and Medicine

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Isoenzyme and protein profiles of normal, leukemic and fetal mouse tissues

Tyndall

Allen

Friedman

et al. 1971

Intl Journal of Cancer

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Electrophoretic characterization of extracts from normal, leukemic and fetal mouse tissues indicated that infection with R L V results in the subsequent emergence of cells having profiles similar to fetal thymus and spleen tissues. Microdensitometric analyses showed diminution of prealbumin and haptoglobin esterase activity with concomitant predominance of postalbumin esterase activity in both fetal and leukemic thymus and spleen tissues. Both JLS V9 and J L S V6 infected cell cultures showed marked enhancement of postalbumin esterase activity. Leukemic and fetal thymus and spleen tissues also showed increased activity in LDH isoenzyme V, relative to the total L DH activity, compared to normal adult tissues. Increased relative activity in Band V LDH was also noted in infected V6 cells compared to uninfected cells. Increased amounts of proteins with electrophoretic mobilities similar to serum albumin and transferrin were evident in extracts of fetal and leukemic thymus and spleen tissues. Protein profiles of purified R L V showed a predominant band migrating similarly to serum albumin with minor bands migrating similarly to serum transferrin and haptoglobin.

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Further observations on in vitro cytopathic effects associated with murine leukemia virus infection

Abstract: The previously reported cytopathic effects (CPE)

Cited by 10 publications

References 8 publications

The combined action of rauscher leukemia virus and lactic dehydrogenase virus on mouse lymphatic tissue

The combined action of rauscher leukemia virus and lactic dehydrogenase virus on mouse lymphatic tissue

E. coli Agglutinating Activity of Ulcerative Colitis Sera

Isoenzyme and protein profiles of normal, leukemic and fetal mouse tissues

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