1976
DOI: 10.1002/jbm.820100604
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Further experimental and clinical experience with aluminum oxide endoprostheses

Abstract: This paper describes the design principles of a new endoprosthesis made of dense aluminum oxide (A12O3) and implanted without bone cement. Mechanical tests and animal experiments have proved the sufficient mechanical strength of the bone-prosthesis connection as well as the biocompatibility of the material. So far, 12 tumor patients selected according to strict indication criteria have been operated on. Both the clinical-radiologic and the first histological findings available are encouraging. Special referenc… Show more

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Cited by 41 publications
(7 citation statements)
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“…Alumina ceramic-on-ceramic THR has been in clinical use for more than 25 years. Initial design-related complications such as fractures of the ball head and breakage of ceramic sockets [45][46][47][48][49] were reduced to a minimum by applying changes at the ball-cone junction and by improving the quality of the ceramic product. polyethylene revision cases, 22 a lower rate of degeneration of macrophages detected when alumina particles were phagocytosed instead of Co-based alloy particles, 11,35 and better chemotaxis and less necrosis of alumina-laden macrophages.…”
Section: Discussionmentioning
confidence: 99%
“…Alumina ceramic-on-ceramic THR has been in clinical use for more than 25 years. Initial design-related complications such as fractures of the ball head and breakage of ceramic sockets [45][46][47][48][49] were reduced to a minimum by applying changes at the ball-cone junction and by improving the quality of the ceramic product. polyethylene revision cases, 22 a lower rate of degeneration of macrophages detected when alumina particles were phagocytosed instead of Co-based alloy particles, 11,35 and better chemotaxis and less necrosis of alumina-laden macrophages.…”
Section: Discussionmentioning
confidence: 99%
“…The British surgeon Sir William Arbuthnot Lane (1856–1943) together with British Dame Agnes Gwendoline Hunt (1866–1948), the world's first orthopedic nurse, and the Belgian surgeon Albin Lambotte (1866–1955) designed a fracture plate made of stainless steel 3 . The development of implant materials continues with titanium in the 1940s and 1950s 4 through ceramics (1975) 5–9 to polymers in dentistry and in spinal applications (since the 1980s) 10,11 …”
Section: Introductionmentioning
confidence: 99%
“…Since the early 70s high-density alumina ceramic has been used as a replace ment for metallic femoral articulating components in some of the prosthetic designs [61,62]. The tribological advantage of a polyethylene/alumina configura tion over a polyethylene/metal articulating system has been demonstrated in many laboratory studies in dry and wet conditions [50,[63][64][65][66][67].…”
mentioning
confidence: 99%