CorrespondenceOpen vs laparoscopic donor nephrectomy in renal transplantation Sir, We read with interest the recent article on this subject in the European Urology Update Series [1] and agree with the authors that laparoscopy will make kidney donation more attractive, thus increasing the donor pool and reducing organ shortages. The authors do not mention the prospective randomized controlled trial of hand-assisted laparoscopic live donor nephrectomy vs open surgical live donor nephrectomy [2]. This trial reported 47% less analgesic use, a 35% shorter hospital stay, a more rapid return to non-strenuous activity by 33%, a quicker return to work by 23%, and 73% less pain 6 weeks after the hand-assisted than after the open procedure. Compared with 'pure' laparoscopy, hand-assistance seems to have three advantages, i.e. a shorter warm ischaemia time (and thus less delayed graft function), fewer ureteric complications and a shorter operating time. Although the hand-assisted device adds to the total cost, it is a small price to pay for these clinical advantages. The midline incision used for inserting the hand is small (roughly the surgeon's glove size in cm) and less painful than a flank incision. It seems to be the way forward for live-donor nephrectomies, particularly in view of the above randomized trial. The one criticism of the trial [2] was the lack of blinding, as was used in the randomized, single-blind comparison of laparoscopic vs small-incision cholecystectomy, which showed no advantage in the laparoscopic group [3]. To the pedantic surgeon and critic this will continue to be the subject of debate in the future.
P. Dasgupta, MSc(Urol), MD, DLS, FRCS(