2000
DOI: 10.1001/archderm.136.8.1019
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Further Evidence for an Association of HLA-DR7 With Basal Cell Carcinoma on the Tropical Island of Saba

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Cited by 13 publications
(6 citation statements)
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“…Low levels or absence of expression of class I antigens may result in escape from regulation by cytotoxic T cells, which then facilitates tumor growth (73). Evidence for the involvement of HLA genes in the development of skin cancers was provided by Bouwes Bavinck et al These authors showed that the presence of HLA-DR7 and a decrease of HLA-DR4 are significantly associated with BCC (74). This corroborates the previous finding of Rompel et al that HLA-DR4 is decreased in BCC, especially in patients with multiple BCCs located on the trunk.…”
Section: Human Leukocyte Antigen (Hla)supporting
confidence: 75%
“…Low levels or absence of expression of class I antigens may result in escape from regulation by cytotoxic T cells, which then facilitates tumor growth (73). Evidence for the involvement of HLA genes in the development of skin cancers was provided by Bouwes Bavinck et al These authors showed that the presence of HLA-DR7 and a decrease of HLA-DR4 are significantly associated with BCC (74). This corroborates the previous finding of Rompel et al that HLA-DR4 is decreased in BCC, especially in patients with multiple BCCs located on the trunk.…”
Section: Human Leukocyte Antigen (Hla)supporting
confidence: 75%
“…The association between various HLA antigens and BCC risk has been reported by a number of publications (Bavinck et al 2000; Bouwes Bavinck et al 1997; Bouwes Bavinck et al 1991; Cerimele et al 1988; Czarnecki et al 1991; Myskowski et al 1985). However, the association of this pathway was not validated using the skin eQTLs and is upon further replication.…”
Section: Discussionmentioning
confidence: 87%
“…The low levels or absence of expression of class I antigens may result in escape from recognition by cytotoxic T cells, which then facilitates tumour growth. 159 Evidence for the involvement of HLA genes in the development of skin cancer was provided by Bouwes Bavinck et al 160 These authors showed that the presence of HLA-DR7 and a decrease of HLA-DR4 are significantly associated with BCC. This corroborates the previous finding of Rompel et al 161 that HLA-DR4 is decreased in BCC, especially in patients with multiple BCCs located on the trunk.…”
Section: Human Leucocyte Antigen (Hla) Haplotypesmentioning
confidence: 99%