Furoquinoline Alkaloids of Teclea ouabanguiensis

Abstract

From the stem bark of Teclea ouabanguiensis Aubrev. & Perr. (Rutaceae), six furoquinoline alkaloids have been isolated and characterized. Previously known alkaloids, but new to this plant, were tecleaverdoomine (1), tecleine (3), flindersiamine (4), montrifoline (nkolbisine) ( 5) and kokusaginine (6), while tecleamine 2 is reported from a natural source for the first time. Spectroscopic and chemidal evidence is presented for the structure of the new isolate 2.

A Contribution to the Phytochemistry ofZanthoxylum tessmannii1

“…Not withstanding that these alkaloids are typical of the genus Zanthoxylurn as a whole, they concluded that Z. tessrnannii (as F. tessmannii) is conspecific with Z. gilletii. As part of our investigations on Cameroonian Rutaceae of medicinal interest (7,8,9) and in the hope of clarifying the taxonomic position of Z. tessrnannii, we investigated in detail the alkaloidal as well as the neutral components of the root bark of Z. tessmannii from three localities. We report herein the results of our study.…”

Furoquinoline alkaloids of Ertela (Monnieria) trifolia (L.) Kuntze from the Suriname rainforest

“…A sample of AR5 was then supplied by Dr. Al-Rehaily and investigated by MS and NMR spectroscopy. These data indicated that it was in fact nkolbisine (13) (Ayafor et al, 1982).…”

Antiplasmodial activities of furoquinoline alkaloids from Teclea afzelii

“…1). These six compounds were identifi ed as kokusaginine (1) (Al-Rehaily et al, 2003), tecleaverdoornine (2) (Ayafor et al, 1982), maculine (3) (Yenesew and Dagne, 1988) and montrifoline (4) (Wondimu et al, 1988) together with lupeol (Hafez et al, 1988) and β-sitosterol glucopyranoside (6) (Seo et al, 1978) by comparison of 1D and 2D NMR data with reported data.…”