Furanocoumarins in the Roots of Heracleum Persicum Desf.

The effect of hydroalcoholic extract of angelica (Heracleum persicum) fruit on performance, immune responses, small intestine histology, haematological parameters and carcass characteristics of broiler chickens

“…The antioxidative properties of plant extracts can positively affect the secretion of endogenous digestive enzymes and influence the blood metabolites (Lee et al 1995;Grassmann et al 2000). According to the previous phytochemical investigations, furanocoumarins and flavonoids are among the constituents of Heracleum persicum (Ghodsi 1976;Aynehchi et al 1978;Merijanian et al 1980). Therefore, the possible hypocholesterolemic activity of this plant may be attributed, at least in part, to the presence of flavonoids, as these phytochemicals have been reported to exert numerous activities, including lipid-lowering effects (Kim et al 2009;Li et al 2009;Zhou et al 2009).…”

Anti-inflammatory and analgesic properties of Heracleum persicum essential oil and hydroalcoholic extract in animal models

“…Hydroalcoholic extract of Heracleum persicum contains several furanocoumarins including sphondin (Aynehchi et al, 1978;Souri et al, 2004) and it has been reported that sphondin inhibits IL-1 beta-induced cyclooxygenase-2 expression (Yang et al, 2002). Since this enzyme has a key role in pain and inflammation, it may explain the observed effects of HPHE.…”

“…Pimpinellin, isopimpinellin, bergapten, isobergapten and sphondin are furanocoumarins which are reported from roots of this plant (Aynehchi et al, 1978). There is a report that showed the presence of six furanocoumarins (Merijanian et al, 1980) in the fruits of Heracleum persicum.…”

Composition of Essential Oil of Heracleum persicum Fruits

“…A search through the literature revealed that roots of H. persicum have been investigated on their content of furanocoumarins; five such compounds were isolated and identified (2). Another paper (3) dealt with the presence of such compounds in leaves and seeds of this species: from the seeds six furanocoumarins were isolated, two of which were also found in the teayes.…”