Funktionsuntersuchungen des Herzens mit der Elektronenstrahltomographie

Becker, Alexander; Becker, C.; Knez, Andreas; Haberl, Ralph; Brüning, R.; Reiser, Maximilian; Steinbeck, Gerhard

doi:10.1007/s001170050458

Cited by 6 publications

(1 citation statement)

References 12 publications

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“…Magnetic resonance angiography of coronary arteries with limited spatial resolution yet has still restricted diagnostic value [2,3]. Electron beam tomography as non-invasive technique with high temporal and spatial resolution requires a dedicated specialized hardware and may lead to relatively high radiation doses [4,5].…”

Section: Introductionmentioning

confidence: 99%

Radiation Exposure in Multi-Slice CT of the Heart

Cohnen¹

2001

Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr

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Summary. Purpose: To assess radiation exposure of patients undergoing Multi-Row Detector CT (Multi-Slice CT, MSCT) of the heart. Material and Methods: Four different cardiac MSCT protocols with changing slice collimation (4 1, and 4 2.5 mm), and pitch-factor (1.5, 1.8, and 4) were examined. An anthropomorphic Alderson-Rando phantom was equipped with LiF-thermoluminescent dosimeters at several organ sites, and effective doses were calculated using ICRP-weighting factors. These data were compared to data from standard MSCT of chest and abdomen. Results: Effective dose in different protocols for cardiac MSCT varies from 2.8 to 10.3 mSv (male), and from 3.6 to 12.7 mSv (female). In protocols with thin collimation and low pitch or a combination of several heart examinations, radiation exposure may be comparable to the effective dose of standard MSCT of the chest (male: 11.9 mSv, female: 12.9 mSv) or the abdomen (male: 16.1 mSv, female: 15.7 mSv). Highest organ doses were found for the female breast (up to 46.6 mGy), and the lungs (up to 36.4 mGy) with surface doses as high as 54.3 mGy. Conclusions: Cardiac MSCT adds significantly to the radiation exposure of patients and can reach the effective dose applied by standard MSCT of chest or abdomen. Schlüsselwörter: Strahlenexposition ± Mehrschicht-Spiral CT ± Herz ± Effektive Dosis ± Kardio CT

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Section: Introductionmentioning

confidence: 99%

Radiation Exposure in Multi-Slice CT of the Heart

Cohnen¹

2001

Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr

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Mapping ischemic risk region and necrosis in the isolated heart using EPR imaging

Murugesan

Kuppusamy

et al. 2003

Magnetic Resonance in Med

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Reperfusion of ischemic tissue is a common event in the treatment of heart attack and stroke. To study disease pathogenesis, methods are required to measure tissue perfusion and area at risk, as well as localized regions of injury. While histology can provide this information, its destructive nature precludes assessment of time course. Thus, there is a critical need for a noninvasive technique to obtain this information. To map myocardial redox state as a possible index of cellular ischemia and viability, electron paramagnetic resonance (EPR) imaging experiments were performed on isolated rat hearts before and after the onset of regional ischemia using nitroxide spin labels. With coronary artery occlusion, the EPR images clearly showed the risk region as a void of lower intensity that reversed upon reperfusion. The extent of risk region in the heart was similar in EPR imaging and histological measurements. The unique information obtained regarding the time course of changes in redox metabolism of the risk region and normal myocardium can provide important insights regarding the mechanisms of myocardial injury during and following ischemia.

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