Funktionelle Spätergebnisse nach Lungenresektion

Muhar, F; Kaik, G; A, Kretschy; Raber, A; Scheiblechner, H

doi:10.1007/bf02100538

Cited by 1 publication

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“…Right-to-left shunting responsible for paCT decrease may occur predominantly in the tumor region due to atelectasis [14]. This seems to be the cause of the fact that patients after pneumonectomy usually ex hibit high paOi values at rest [28]. Our pa tients with COPD without lung cancer showed a modest inverse correlation be tween exercise tolerance and pa02 de crease from rest to exercise (r = -0.5), whereas the patients with lung cancer and COPD exhibited no correlation between these variables (r = 0.02).…”

Section: Mechanisms Of Paü2 Response During Exercisementioning

confidence: 99%

Pulmonary Gas Exchange and Central Hemodynamics at Rest and during Exercise in Patients with Chronic Obstructive Pulmonary Disease

Seibold¹,

Roth²,

Lippert³

et al. 1986

Respiration

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Right-heart catheterization and ergometry with arterial and mixed venous blood gas analysis were performed in 27 patients with a wide range of chronic obstructive pulmonary diseases. The purpose of the examination was to evaluate the risk in patients for lung surgery or to detect additional heart diseases. Patients who developed ex-ertional hypoxia (group 1) were compared with others who did not (group 2). In all patients the steady-state maximal workload was determined by ventilatory dysfunction. Both groups had normal values for mixed venous pO₂ and normal increase of the circulatory parameters during exercise. The patients with exertional hypoxia differed from the others in that they showed no decrease of venous admixture and alveolar-arterial oxygen gradient. In addition, these patients had increasing pCO₂ values at rest compared with exercise, indicating alveolar hypoventilation and ventilation-perfusion mismatching. Because of the good correlation of the absolute values of FEV₁ (forced expiratory volume in 1 s) with pulmonary artery pressures, parameters of gas exchange and working capacity, this lung function parameter seems to have a central role in predicting the functional state of patients with chronic obstructive disease. Ergometry and blood gas analysis should be performed in addition because these values cannot be predicted with the calculated postoperative FEV₁

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Section: Mechanisms Of Paü2 Response During Exercisementioning

confidence: 99%