Fungicidal properties and insights on the mechanisms of the action of volatile oils from Amazonian Aniba trees

Souza, Diogo de; Pimentel, Renah Boanerges de Queiroz; Santos, Alberdan Silva; Albuquerque, Patrícia Melchionna; Fernandes, Andréia Varmes; Junior, Sergio D.; Oliveira, José T.A.; Ramos, Márcio V.; Rathinasabapathi, Bala; Gonçalves, José Francisco de Carvalho

doi:10.1016/j.indcrop.2019.111914

Cited by 24 publications

(24 citation statements)

References 88 publications

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“…This sample displayed 26 compounds that were satisfactorily identified, comprising more than 99 % of the EO composition. The oxygenated aliphatic monoterpene linalool (16.3±3.15 %) was the main compound of this EO, as already observed for leaves and branches of A. parviflora , [12] as well as in other species of Aniba [16] . Other main compounds were α ‐humulene (14.5±2.41 %), δ ‐cadinene (10.2±1.09 %), α ‐copaene (9.51±1.12 %) and germacrene B (7.58±2.15 %).…”

Section: Resultssupporting

confidence: 69%

Essential Oil from Bark of Aniba parviflora (Meisn.) Mez (Lauraceae) Reduces HepG2 Cell Proliferation and Inhibits Tumor Development in a Xenograft Model

Oliveira

Rodrigues

Lima

et al. 2021

Chemistry & Biodiversity

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Aniba parviflora (Meisn.) Mez (Lauraceae) is an aromatic plant of the Amazon rainforest, which has a tremendous commercial value in the perfumery industry; it is popularly used as flavoring sachets and aromatic baths. In Brazilian folk medicine, A. parviflora is used to treat victims of snakebites. Herein, we analyzed the chemical composition of A. parviflora bark essential oil (EO) and its effect on the growth of human hepatocellular carcinoma HepG2 cells in vitro and in vivo. EO was obtained by hydrodistillation and characterized by GC‐MS and GC‐FID. The main constituents of EO were linalool (16.3±3.15), α‐humulene (14.5±2.41 %), δ‐cadinene (10.2±1.09 %), α‐copaene (9.51±1.12 %) and germacrene B (7.58±2.15 %). Initially, EO's cytotoxic effect was evaluated against five cancer cell lines (HepG2, MCF‐7, HCT116, HL‐60 and B16‐F10) and one non‐cancerous one (MRC‐5), using the Alamar blue method after 72 h of treatment. The calculated IC50 values were 9.05, 22.04, >50, 15.36, 17.57, and 30.46 μg/mL, respectively. The best selectivity was for HepG2 cells with a selective index of 3.4. DNA Fragmentation and cell cycle distribution were quantified in HepG2 cells by flow cytometry after a treatment period of 24 and 48 h. The effect of EO on tumor development in vivo was evaluated in a xenograft model using C.B‐17 SCID mice engrafted with HepG2 cells. In vivo tumor growth inhibition of HepG2 xenograft at the doses of 40 and 80 mg/kg were 12.1 and 62.4 %, respectively.

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Section: Resultssupporting

confidence: 69%

Essential Oil from Bark of Aniba parviflora (Meisn.) Mez (Lauraceae) Reduces HepG2 Cell Proliferation and Inhibits Tumor Development in a Xenograft Model

Oliveira

Rodrigues

Lima

et al. 2021

Chemistry & Biodiversity

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“…Recently, it was identified that Aniba essential oils disrupted the cell membrane of all eight phytopathogen types including Aspergillus flavus, Aspergillus niger and Fusarium solani by triggering more nucleic acid and protein productions [39]. Vitex Negundo essential oil is introduced to fight against Avena fatua and Echinochloa crus-galli weeds.…”

Section: Surfactant As An Emulsifier In Nanoemulsionmentioning

confidence: 99%

Synthesis and Technology of Nanoemulsion-Based Pesticide Formulation

2020

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Declines in crop yield due to pests and diseases require the development of safe, green and eco-friendly pesticide formulations. A major problem faced by the agricultural industry is the use of conventional agrochemicals that contribute broad-spectrum effects towards the environment and organisms. As a result of this issue, researchers are currently developing various pesticide formulations using different nanotechnology approaches. The progress and opportunities in developing nanoemulsions as carriers for plant protection or nanodelivery systems for agrochemicals in agricultural practice have been the subject of intense research. New unique chemical and biologic properties have resulted in a promising pesticide nanoformulations for crop protection. These innovations—particularly the nanoemulsion-based agrochemicals—are capable of enhancing the solubility of active ingredients, improving agrochemical bioavailability, and improving stability and wettability properties during the application, thus resulting in better efficacy for pest control and treatment. All of these—together with various preparation methods towards a greener and environmentally friendly agrochemicals—are also discussed and summarized in this review.

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“…EOs antimicrobial activity exploitable in the control of phytopatogenic diseases is due to these single constituents and their synergistic interactions [104]. Lipophilic volatile molecules of EOs penetrate the cell wall and damage cell membranes by altering permeability and seal and affect morphology, growth, reproductive functions and viability of microorganisms [105]. An injured plasma membrane may result in a leakage of cellular components, including nucleic acids and proteins, and cellular collapse until death, representing the mode of action underlying the biostatic and biocidal EOs effects [106].…”

Section: Sage Essential Oilsmentioning

confidence: 99%

Sage Species Case Study on a Spontaneous Mediterranean Plant to Control Phytopathogenic Fungi and Bacteria

Zaccardelli

Pane

Caputo

et al. 2020

Forests

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Sage species belong to the family of Labiatae/Lamiaceae and are diffused worldwide. More than 900 species of sage have been identified, and many of them are used for different purposes, i.e., culinary uses, traditional medicines and natural remedies and cosmetic applications. Another use of sage is the application of non-distilled sage extracts and essential oils to control phytopathogenic bacteria and fungi, for a sustainable, environmentally friendly agriculture. Biocidal propriety of non-distilled extracts and essential oils of sage are w documented. Antimicrobial effects of these sage extracts/essential oils depend on both sage species and bacteria and fungi species to control. In general, it is possible to choose some specific extracts/essential oils to control specific phytopathogenic bacteria or fungi. In this context, the use of nanotechnology techniques applied to essential oil from salvia could represent a future direction for improving the performance of eco-compatible and sustainable plant defence and represents a great challenge for the future.

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Fungicidal properties and insights on the mechanisms of the action of volatile oils from Amazonian Aniba trees

Cited by 24 publications

References 88 publications

Essential Oil from Bark of Aniba parviflora (Meisn.) Mez (Lauraceae) Reduces HepG2 Cell Proliferation and Inhibits Tumor Development in a Xenograft Model

Essential Oil from Bark of Aniba parviflora (Meisn.) Mez (Lauraceae) Reduces HepG2 Cell Proliferation and Inhibits Tumor Development in a Xenograft Model

Synthesis and Technology of Nanoemulsion-Based Pesticide Formulation

Sage Species Case Study on a Spontaneous Mediterranean Plant to Control Phytopathogenic Fungi and Bacteria

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