Fungal Septicemia in Surgical Patients

Abstract

Opportunistic systemic fungal infections are more frequent than generally realized. Increased awareness and a high index of suspicion of fungal super-infection in the presence of sepsis is required to bring about recognition and therapy. The intravenous catheter is an important portal of entry or may act as a foreign body favoring localization of a septic process. In its presence, fungemia must be guarded against. Whenever an intravenous catheter is removed, its tip should be cultured. Removal alone may be a critical item in therapy. In febrile patients, in whom the course of fever is not established, frequent blood cultures with attention directed specifically at fungi should be obtained. Fungi are not easily isolated and identified and only by requesting special attention from the microbiologist can the diagnosis be established in the average institutional laboratory in time to permit appropriate therapy. Since available therapeutic measures are strikingly effective when instituted early, awareness and alertness on the part of the clinician constitute the key to cure.

Candida Peritonitis: An Update on the Latest Research and Treatments

“…Extreme youth or old age [120] 4. Poor nutritional status [120] 5. Total parenteral nutrition [1,120] 6.…”

“…Poor nutritional status [120] 5. Total parenteral nutrition [1,120] 6. Critical care patients [1] 7.…”

“…HIV, leading to increased frequency of esophageal candidiasis, placing the patients at risk for invasive Candida infections [2] 19. Transplantation [2,120] 20. Trauma [120] 21.…”

“…Colonization with Candida species, especially candiduria, hospitalacquired candidemia, especially in the ICU setting, and mechanical ventilation [1,2,18,21,32] 2. Previous antibiotic use [75,120] 3. Extreme youth or old age [120] 4.…”

“…Previous antibiotic use [75,120] 3. Extreme youth or old age [120] 4. Poor nutritional status [120] 5.…”