Fungal liver abscess in an immunocompetent patient who underwent repeated ERCPs and subtotal cholecystectomy

Hasan, Sundas; Fearn, Robert

doi:10.1136/bcr-2017-222013

Cited by 6 publications

(6 citation statements)

References 13 publications

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“…Pancreatic fungal infections occur in patients with severe acute pancreatitis, 7 a history of surgical manipulation of the abdomen after an episode of acute pancreatitis, ERCP, 8 total parenteral nutrition, and mechanical ventilation. 9 An altered host immune system due to chemotherapy, steroid therapy, comorbid diabetes mellitus, and advanced age is also a predisposing risk factor for pancreatic fungal infections.…”

Section: Discussionmentioning

confidence: 99%

Primary Pancreatic Candidiasis Mimicking Pancreatic Cancer in an Immunocompetent Patient

Kim

Lee

Woo

et al. 2021

Korean J Gastroenterol

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Pancreatic candidiasis can develop in patients with acute pancreatitis, compromised immune responses, or iatrogenic intervention. This paper reports a case of pancreatic candidiasis presenting as a solid pancreatic mass in a patient without the risk factors. A previously healthy 37-year-old man visited the emergency department with left flank pain. Abdominal CT revealed a 5 cm, irregular heterogeneous enhancing mass accompanied by a left adrenal mass. Positron emission tomography-computed tomography and endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) could not discriminate pancreatic cancer from infectious disease. A laparoscopic exploration was performed for an accurate diagnosis. After distal pancreatectomy with splenectomy and left adrenalectomy, pancreatic candidiasis and adrenal cortical adenoma were diagnosed based on the pathology findings. His condition improved after the treatment with fluconazole. This paper reports a case of primary pancreatic candidiasis mimicking pancreatic cancer in an immunocompetent patient with a review of the relevant literature.

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Section: Discussionmentioning

confidence: 99%

Primary Pancreatic Candidiasis Mimicking Pancreatic Cancer in an Immunocompetent Patient

Kim

Lee

Woo

et al. 2021

Korean J Gastroenterol

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“…However, the causative species was Candida dubliniensis in this case [ 9 ]. Menachery et al and Hasan et al both reported a solitary C. albicans liver abscess in their patients [ 10 , 11 ]. However, the patient reported by Hasan et al developed the liver abscess primarily as a complication of repeated endoscopic retrograde cholangiopancreatography (ERCP) and subtotal cholecystectomy [ 11 ].…”

Section: Discussionmentioning

confidence: 99%

“…Menachery et al and Hasan et al both reported a solitary C. albicans liver abscess in their patients [ 10 , 11 ]. However, the patient reported by Hasan et al developed the liver abscess primarily as a complication of repeated endoscopic retrograde cholangiopancreatography (ERCP) and subtotal cholecystectomy [ 11 ]. Furthermore, as in our patient, respiratory symptoms as the primary presenting complaint have not been documented before, and thus physicians should remain cognizant of this unique presentation.…”

Section: Discussionmentioning

confidence: 99%

Hepatic Candidiasis in an Immunocompetent Patient: A Diagnostic Challenge

Moazzam

Yousaf

Iqbal

et al. 2021

Cureus

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Hepatic candidiasis is a manifestation of disseminated candidiasis, which typically presents in immunocompromised patients. Focal hepatic candidiasis in immunocompetent patients, however, is infrequent/extremely rare. We present the case of an immunocompetent female patient who presented with respiratory distress and right-sided pleural effusion. The pleural fluid tap did not grow anything, and a contrast-enhanced computed tomography (CT) scan revealed a right liver lobe subcapsular collection. CTguided aspiration and culture resulted in Candida albicans growth. The patient responded to oral fluconazole, and a follow-up CT scan demonstrated resolution of the collection. Although hepatic candidiasis rarely occurs in immunocompetent patients, it should be included in the differential diagnosis of hepatic abscesses, as timely diagnosis and management are crucial in conferring a good prognosis.

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“…Vancomycin is typically reserved for the patient in septic shock or cases where staphylococcus aureus may be a concern [30,31]. Fluconazole is commonly added in the rare event that the abscess is of fungal etiology [32].…”

Section: Medical Treatmentmentioning

confidence: 99%

The Silent Killer: A Case Report of Delayed Diagnosis and Successful Treatment of Pancreatic Trauma

Coral

2023

oajs

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Hepatic abscesses are suppurated cavities caused by the invasion and multiplication of microorganisms within the liver parenchyma. This condition is relatively uncommon, with an estimated incidence of 2.3 to 3.6 cases per 100,000 people yearly. However, the incidence is higher in specific populations, such as patients with underlying liver disease, diabetes, or other immune-compromising conditions. The most common cause of liver abscesses is the spread of infection from other parts of the body, such as the biliary tract or gastrointestinal tract. Other causes include trauma to the liver, such as from a penetrating injury or surgery or the presence of a foreign body in the liver. Liver abscesses are broadly divided into two types: amoebic and pyogenic. The clinical presentation might vary, including fever, abdominal pain, nausea and vomiting, jaundice, and weight loss. In some cases, there may be no symptoms. Diagnosis typically involves an ultrasound or CT scan, which can show the presence of a fluid-filled mass in the liver. CT is the standard modality for diagnosis. Blood tests may also evaluate liver function and identify any underlying infections. Treatment typically involves a combination of antibiotics to target the underlying infection and drainage of the abscess. Supportive measures like hydration and pain management may also be necessary. In addition, close monitoring and follow-up are essential to ensure that the abscess has resolved and there are no complications. In some cases, surgical intervention may be necessary to remove the abscess or repair any damage to the liver. Liver abscess drainage is typically indicated in patients with significant, symptomatic abscesses or those who do not respond to medical treatment with antibiotics. In addition, abscesses at risk of rupturing or located close to vital structures, such as major blood vessels, may require drainage to prevent serious complications. Two drainage methods are presently available: non-surgical options, such as percutaneous needle aspiration or percutaneous catheter drainage, and surgical options, such as open drainage or laparoscopic drainage. This review identifies when these alternatives should be used, taking adverse effects, symptoms, and comorbidities into account.

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Fungal liver abscess in an immunocompetent patient who underwent repeated ERCPs and subtotal cholecystectomy

Cited by 6 publications

References 13 publications

Primary Pancreatic Candidiasis Mimicking Pancreatic Cancer in an Immunocompetent Patient

Primary Pancreatic Candidiasis Mimicking Pancreatic Cancer in an Immunocompetent Patient

Hepatic Candidiasis in an Immunocompetent Patient: A Diagnostic Challenge

The Silent Killer: A Case Report of Delayed Diagnosis and Successful Treatment of Pancreatic Trauma

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