Fungal Infections

Vázquez, José Antonio

doi:10.1002/9781118063842.ch12

Cited by 1 publication

(1 citation statement)

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“…It was first reported as a cause of human disease by Paltauf in 1885 [6]. Other filamentous fungi infect hosts with marked immunodeficiency, but Zygomycosis is unique in that it infects a wider group of individuals, including fully immunocompetent hosts [7][8].…”

Section: Introductionmentioning

confidence: 99%

Zygomycoses - urgency in diagnosis

Abraham

Oberoi

Dewan

et al. 2015

IJBAS

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Introduction: Zygomycoses is an angioinvasive infection most commonly seen in immunocompromised and diabetic patients. We undertook this study to determine the prevalence of Zygomycoses, in patients with a suspected Invasive Zygomycoses Infection in a tertiary centre and to identify the most common species isolated from culture. Materials and Methods: A retrospective analysis was done from January 1, 2012 to December 8, 2014; the clinical data of the suspected patients and the positive cultures were collected. Results and Discussion: A total of 50 samples of 27 patients with suspected Zygomycoses were sent during the 3 year period. In 25 of these patients, the samples sent were tissue biopsies from nasal cavity and 2 wound swabs from burns. Of these, 18 tissue biopsies of 13 patients and two wound swabs were detected positive for Zygomycetes. (2-Absidia corymbifera; 1-Rhizopus, 15-Mucor). Of the remaining 12 patients whose cultures were negative, 1-bacterial 1-bacterial sinusitis, 5-Invasive aspergillosis; 6-treated as Invasive fungal infections due to Zygomycetes as the imaging diagnostics and histopathological features favored that diagnosis. The majority of the patients (80%) were diabetic, and the two from the burn unit were under long-term treatment for chronic wound infections. Multiple diagnostic modalities must be used in view of the aggressive nature of the disease, but microbiological diagnosis remains the Gold Standard.

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Section: Introductionmentioning

confidence: 99%