Fungal Endophthalmitis Following Intraocular Lens Implantation

Pettit, Thomas H.

doi:10.1001/archopht.1980.01020031015002

Cited by 183 publications

(76 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…lilacinum, an opportunistic and emerging pathogen, has been known to cause infections in persons with both normal and deficient immune system, particularly in patients with indwelling foreign devices or following intraocular lens implants. [9][10][11] Paecilotoxin is the mycotoxin produced from this fungus, but its significance in causing human infection is not known [12]. Some of the infections caused in humans are cutaneous and subcutaneous lesions, vaginitis, endophthalmitis, fungemia, onychomycosis, keratitis, bursitis and sinusitis, etc.…”

Section: Discussionmentioning

confidence: 99%

A Rare Case of Nasal Septal Perforation Due to Purpureocillium lilacinum: Case Report and Review

Shivaprasad

Ravi

Shivapriya

et al. 2012

Indian J Otolaryngol Head Neck Surg

View full text Add to dashboard Cite

Perforations of nasal septum are fairly frequent with an incidence of about 0.9 % and may lead to morbidity than mortality. Common causes are trauma (iatrogenic occasionally nose picking), malignancy, inflammations and infections such as tuberculosis, syphilis, Wegener's granulomatosis, sarcoidosis and fungal infections. Paranasal fungal sinusitis is frequently encountered in clinical practice in both immunocompromised and immunocompetent individuals. Nasal septal perforations caused by species of Aspergillus and Fusarium have been documented. We report a case of nasal septal perforation in a 35-years-old immunocompetent male patient due to Purpureocillium lilacinum, a soil and environmental fungus and an emerging pathogen, which is known to cause various infections in humans with normal and deficient immune system. Fungal aetiology was diagnosed by histopathology and direct smear examination and confirmed by culture. Patient was treated with voriconozole, following Antifungal susceptibility testing (AFST), to which the patient is responding.

show abstract

Section: Discussionmentioning

confidence: 99%

A Rare Case of Nasal Septal Perforation Due to Purpureocillium lilacinum: Case Report and Review

Shivaprasad

Ravi

Shivapriya

et al. 2012

Indian J Otolaryngol Head Neck Surg

View full text Add to dashboard Cite

show abstract

“…The infiltrate in exogenous fungal endophthalmitis is localised frequently, to the anterior chamber, papillary space or anterior vitreous. 4 Treatment with prolonged topical steroids for a painless postoperative low-grade anterior uveitis secondary to fungal endophthalmitis is not untypical. 5,6 Amphotericin B has low penetration as a topical agent and in patients without signs or symptoms of nonocular candidiasis withholding systemic amphotericin can be considered in view of potential side effects.…”

Section: Discussionmentioning

confidence: 99%

A case of postoperative candida endophthalmitis

Lagnado

Gupta

Osborne

et al. 2004

Eye

View full text Add to dashboard Cite

Further topical therapy was given and the right IOP fell to 32 mmHg, but the patient still complained of feeling unwell. The IOP in his left eye was checked and found to be 52 mmHg with an associated shallow anterior chamber. A diagnosis of acute angle closure glaucoma was made. Further systemic and topical treatment was given and the respective IOPs fell to 31 and 21 mmHg in the right and left eyes with associated relief of the symptoms. A left YAG peripheral iridotomy was subsequently performed. CommentThe most likely cause of the acute glaucoma in the unoperated eye was the prolonged posturing in the face down position. Indeed, one provocative test for glaucoma is to place patients in the prone position. 2 The mechanism for this is the shifting of the lens-iris diaphragm anteriorly. This shallows the anterior chamber and narrows the angle. In our patient, the problem was compounded by the dilatation of the eye. Although it is unlikely that the episode of angle closure was solely precipitated by dilatation as both eyes had been dilated previously at vitreo-retinal clinic without incident. Also, gonioscopy had found a slightly narrow angle and the axial length was not particularly short. Biometry prior to the cataract surgery found axial lengths of 24 and 23.7 mm in the right and left eyes, respectively. Furthermore, it is unlikely that there was a phacomorphic component as there was no significant cataract in the left eye.Raised IOPs can, therefore, be found in both the operated and unoperated eyes following pars plana vitreous surgery. Indeed for the unoperated eye this is not surprising, as vitreoretinal surgery often requires prone posturing and dilatation, both of which may precipitate angle closure glaucoma in those at risk.

show abstract

“…Previously, a series of 13 cases of fungal endophthalmitis were reported to be attributed to the use of contaminated BSS solutions. 4 Eight of the 13 eyes required enucleation. Fortunately, our patient did not develop endophthalmitis.…”

Section: Commentmentioning

confidence: 99%