Fungal endocarditis

Ankola, Pratibha; Perveen, Shahana; Fish, Bernard G.

doi:10.1038/sj.jp.7211557

Cited by 4 publications

(4 citation statements)

References 11 publications

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“…Management of fungal endocarditis in premature infants is controversial. Use of prolonged anti-fungal therapy in conjunction with surgical removal of thrombus is shown to be an effective approach to the treatment of this complication [10]. Use of prolonged anti-fungal treatment alone is reported in few critically ill infants with fungal endocarditis [11].…”

Section: Discussionmentioning

confidence: 99%

Premature newborn with intracardiac fungus balls and endocarditis which is curable only with anti-fungal therapy: Case presentation

Çetin¹,

Özen²,

Yıldırımer³

et al. 2013

CRCM

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Invasive fungal infections often caused by Candida species are infections which have high morbidity and mortality rates in newborn infants. 5% of the cases have also concomitant endocarditis and this causes mortality rates over 60%. Thus it has vital importance to diagnose and treat these patients with endocarditis in early stages. Most preferred treatment option is a surgical incision in addition to systemic anti-fungal therapy. Here we presented an extremely low birth weight, premature newborn with endocarditis caused by Candida tropicalis and cured solely by systemic anti-fungal treatment without the need for surgical intervention.

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Section: Discussionmentioning

confidence: 99%

Premature newborn with intracardiac fungus balls and endocarditis which is curable only with anti-fungal therapy: Case presentation

Çetin¹,

Özen²,

Yıldırımer³

et al. 2013

CRCM

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“…Multiorgan involvement, apart from endocardium, was reported in 15 cases. 5,15,22,28,[34][35][36][37][38]46,48,57,58 The most common non-heart organs affected were the kidneys (9 cases), followed by central nervous system (CNS, 5 cases), liver (3 cases), arterial vessels with skin (2 cases each) and spleen with lung (1 case each). Skin involvement was present as cutaneous abscess and scleroderma.…”

Section: Site Of Vegetation and Microbiologymentioning

confidence: 99%

“…30,48 More recently, recombinant tissue plasminogen activator (r-TPA) was administered as adjunctive therapy with liposomal AMB in 2 neonates with FE (2.8%). 18,41 The first case involved a premature infant (BW: 566 g) with Candida tropicalis endocarditis, and the second case was a premature infant (BW: 800 g) with endocarditis attributed to C. albicans fungemia.…”

Section: Therapymentioning

confidence: 99%

Fungal Endocarditis in Neonates

Pana

Dotis²,

Iosifidis³

et al. 2015

Pediatric Infectious Disease Journal

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“…Systemic fungal infections are an important cause of morbidity, mortality and neuro‐developmental problems in preterm newborns . Fungal endocarditis represent one of the rare complications of systemic fungal infections and its incidence has increased . In preterm newborns, fungal endocarditis have a high mortality and morbidity.…”

Section: Introductionmentioning

confidence: 99%

Treatment of neonatal fungal infective endocarditis with recombinant tissue plasminogen: activator in a low birth weight infant case report and review of the literature

Babayiğit

Cebeci

Büyükkale

et al. 2015

Mycoses

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With advances in medical sciences, an increase in survival rates of low birth weight; increased incidence in use of catheter and antibiotics, and total parenteral nutrition are reported, therefore, the rate of fungal infections in late and very late onset neonatal sepsis have increased. Although fungal endocarditis rarely occur in newborns, it has a high morbidity and mortality. Antifungal therapy is often insufficient in cases who develop fungal endocarditis and surgical treatment is not preferred due to its difficulty and high mortality. Herein, fungal endocarditis in a preterm newborn treated with single-dose recombinant tissue plasminogen activator in addition to antifungal therapy is presented and relevant literature has been reviewed. The vegetation completely disappeared following treatment and no complication was observed.

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Fungal endocarditis

Cited by 4 publications

References 11 publications

Premature newborn with intracardiac fungus balls and endocarditis which is curable only with anti-fungal therapy: Case presentation

Premature newborn with intracardiac fungus balls and endocarditis which is curable only with anti-fungal therapy: Case presentation

Fungal Endocarditis in Neonates

Treatment of neonatal fungal infective endocarditis with recombinant tissue plasminogen: activator in a low birth weight infant case report and review of the literature

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