Abstract:Impact Sentence: Rho GTPase adaptors play unique and sequential roles in the 27 regulation of MAPK pathways. 28 29 Cdc42p Adaptors Regulate a MAPK Pathway Basu et al. 2 HIGHLIGHTS 30• Comparing Cdc42p-dependent MAPK pathways showed that the fMAPK 31 pathway had slow activation kinetics compared to the mating and HOG 32 pathways. 33
34• A collection of cdc42 alleles was tested for MAPK pathway functions. 35 § Cdc42p E100A , previously characterized as being specifically defective for fMAPK 36 signali… Show more
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