Functionalized starch microparticles for contact-active antimicrobial polymer surfaces

Ojogbo, Ewomazino; Ward, Valerie C.A.; Mekonnen, Tizazu H.

doi:10.1016/j.carbpol.2019.115422

Cited by 30 publications

(22 citation statements)

References 31 publications

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“…These materials serve valuable purposes in healthcare, personal care, food management, hygiene products, biomedical devices and surfaces that are highly prone to microbial contamination leading to disease [1,2]. Antimicrobial materials may be used as coatings on medical devices or surgical instruments, on materials that may contact the human body, such as implants or biomedical devices [3,4] and also as antifouling coatings for marine applications [5,6].…”

Section: Introductionmentioning

confidence: 99%

Preparation of Antimicrobial Coatings from Cross-Linked Copolymers Containing Quaternary Dodecyl-Ammonium Compounds

Druvari

Antonopoulou

Lainioti

et al. 2021

IJMS

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One of the concerns today’s societies face is the development of resistant pathogenic microorganisms. The need to tackle this problem has driven the development of innovative antimicrobial materials capable of killing or inhibiting the growth of microorganisms. The present study investigates the dependence of the antimicrobial activity and solubility properties on the hydrophilicity/hydrophobicity ratio of antimicrobial coatings based on quaternary ammonium compounds. In this line, suitable hydrophilic and hydrophobic structural units were selected for synthesizing the antimicrobial copolymers poly(4-vinylbenzyl dimethyldodecylammonium chloride-co-acrylic acid), P(VBCDDA-co-AA20) and poly(dodecyltrimethylammonium 4-styrene sulfonate-co-glycidyl methacrylate), P(SSAmC12-co-GMA20), bearing an alkyl chain of 12 carbons either through covalent bonding or through electrostatic interaction. The cross-linking reaction of the carboxylic group of acrylic acid (AA) with the epoxide group of glycidyl methacrylate (GMA) of these two series of reactive antimicrobial copolymers was explored in blends, obtained through solution casting after curing at various temperatures. The release of the final products in pure water and NaCl 1 M solutions (as analyzed by gravimetry and total organic carbon, TOC/total nitrogen, TN analyses), could be controlled by the coating composition. The cross-linked polymeric membranes of composition 60/40 w/w % ratios led to 97.8 and 99.7% mortality for Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus), respectively, whereas the coating 20/80 w/w % resulted in 96.6 and 99.8% cell reduction. Despite the decrease in hydrophobicity (from a 16- to a 12-carbon alkyl chain), the new materials maintained the killing efficacy, while at the same time resulting in increased release to the aqueous solution.

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Section: Introductionmentioning

confidence: 99%

Preparation of Antimicrobial Coatings from Cross-Linked Copolymers Containing Quaternary Dodecyl-Ammonium Compounds

Druvari

Antonopoulou

Lainioti

et al. 2021

IJMS

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“…modified starch by reaction with an isocyanate‐functional poly(hexamethyleneguanidine) (PHMG). [ 124 ] Films of the resulting material combined with poly(lactic acid) (PLA) showed high antimicrobial activity (see Table 6, entry 6). Furthermore, the resulting materials showed little evidence of PHMG leaching, indicating high immobilization of the bactericide.…”

Section: Preparation Of Antimicrobial Polymers From Common Polymer Materialsmentioning

confidence: 99%

A Synthetic Overview of Preparation Protocols of Nonmetallic, Contact‐Active Antimicrobial Quaternary Surfaces on Polymer Substrates

Andersen

Madsen

Daugaard

2021

Macromol. Rapid Commun.

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Antibacterial surfaces have been researched for more than 30 years and remain highly desirable. In particular, there is an interest in providing antimicrobial properties to commodity plastics, because these, in their native state, are excellent substrates for pathogens to adhere and proliferate on. Therefore, efficient strategies for converting surfaces of commodity plastics into contact‐active antimicrobial surfaces are of significant interest. Many systems have been prepared and tested for their efficacy. Here, the synthetic approaches to such active surfaces are reviewed, with the restriction to only include systems with tested antibacterial properties. The review focuses on the synthetic approach to surface functionalization of the most common materials used and tested for biomedical applications, which effectively has limited the study to quaternary materials. For future developments in the field, it is evident that there is a need for development of simple methods that permit scalable production of active surfaces. Furthermore, in terms of efficacy, there is an outstanding concern of a lack of universal antimicrobial action as well as rapid deactivation of the antibacterial effect through surface fouling.

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“…The methods employed in obtaining antimicrobial activity vary from adding sachets with volatile antimicrobial agents inside current packaging to incorporating the active agent directly into biopolymers and from coating or grafting antimicrobial substances on polymeric surface to the use of intrinsic antimicrobial polymers or antimicrobial pads ( Figure 1 ) [ 38 , 39 , 40 , 41 , 42 ].…”

Section: Introductionmentioning

confidence: 99%

Biodegradable Antimicrobial Food Packaging: Trends and Perspectives

Motelică

Ficai

et al. 2020

Foods

229

134

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This review presents a perspective on the research trends and solutions from recent years in the domain of antimicrobial packaging materials. The antibacterial, antifungal, and antioxidant activities can be induced by the main polymer used for packaging or by addition of various components from natural agents (bacteriocins, essential oils, natural extracts, etc.) to synthetic agents, both organic and inorganic (Ag, ZnO, TiO2 nanoparticles, synthetic antibiotics etc.). The general trend for the packaging evolution is from the inert and polluting plastic waste to the antimicrobial active, biodegradable or edible, biopolymer film packaging. Like in many domains this transition is an evolution rather than a revolution, and changes are coming in small steps. Changing the public perception and industry focus on the antimicrobial packaging solutions will enhance the shelf life and provide healthier food, thus diminishing the waste of agricultural resources, but will also reduce the plastic pollution generated by humankind as most new polymers used for packaging are from renewable sources and are biodegradable. Polysaccharides (like chitosan, cellulose and derivatives, starch etc.), lipids and proteins (from vegetal or animal origin), and some other specific biopolymers (like polylactic acid or polyvinyl alcohol) have been used as single component or in blends to obtain antimicrobial packaging materials. Where the package’s antimicrobial and antioxidant activities need a larger spectrum or a boost, certain active substances are embedded, encapsulated, coated, grafted into or onto the polymeric film. This review tries to cover the latest updates on the antimicrobial packaging, edible or not, using as support traditional and new polymers, with emphasis on natural compounds.

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Functionalized starch microparticles for contact-active antimicrobial polymer surfaces

Cited by 30 publications

References 31 publications

Preparation of Antimicrobial Coatings from Cross-Linked Copolymers Containing Quaternary Dodecyl-Ammonium Compounds

Preparation of Antimicrobial Coatings from Cross-Linked Copolymers Containing Quaternary Dodecyl-Ammonium Compounds

A Synthetic Overview of Preparation Protocols of Nonmetallic, Contact‐Active Antimicrobial Quaternary Surfaces on Polymer Substrates

Biodegradable Antimicrobial Food Packaging: Trends and Perspectives

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