“…Inhibited OGG1 is involved in base excision repair; nucleoplasm, lyase activity, DNA repair, response to endogenous stimulus, carbohydrate metabolism, response to DNA damage stimulus, hydrolase activity and acting on glycosyl bonds (kegg, genmapp); colorectal cancer, cancer of prostate, spinocerebellar ataxia type 1, adenocarcinoma, parkinson disease, chromosome aberrations, carcinoma non-small-cell lung, colorectal carcinoma, skin cancer, glioma, loss of heterozygosity, microsatellite instability, adenocarcinoma of the lung, leukemia, xeroderma pigmentosum, genetic predisposition to disease, carcinoma squamous cell, neurodegenerative diseases, carcinoma of lung, somatic mutations, amyotrophic lateral sclerosis, stomach cancer, dysplasia, acute leukemia, Cockayne syndrome, Alzheimer's disease, ovarian cancer, neoplasms, nerve degeneration, hereditary diseases, malignant neoplasm of endometrium, inflammation, malignant neoplasms, cancer of bladder, malignant neoplasm of lung, cancer recurrence, type ii cockayne syndrome, non-small cell lung cancer, heart failure congestive, adenoma, polyposis, carcinoma, malignant tumor of colon, allelic imbalance, lung neoplasms, adenomatous polyposis coli, malignant neoplasm of breast, primary carcinoma of the liver cells, cholangiocarcinoma, colorectal cancer, lung cancer, Adenocarcinoma of the lung, lung cancer risk, alcohol abuse | smoking behavior, DNA damage, oxidative, stomach cancer, pneumoconiosis, coal workers', gastric cancer, pancreatic cancer, hepatocellular carcinoma, esophageal cancer, pterygium, cervical cancer, neural tube defects | cleft lip with cleft palate | cleft lip without cleft palate, cytogenetic studies, prostate cancer, bladder cancer (disease from CapitalBio MAS 3.0). We inferred lowexpression MAN2B2 metabolism network stronger glutathione metabolism but weaker base-excision repair as a result of inducing cell growth in chimpanzee left cerebrum.We also found evidences from literatures to support the inference[57][58][59][60][61].High-Expression MAN2B2 Metabolism Network Analysis in Human Left CerebrumTenth, we identified the different novel molecules of highexpression MAN2B2 metabolism network in human left cerebrum compared with chimpanzee left cerebrum. The different upstream ATP2B1, SGSH activated MAN2B2, and GSTM5, OGG1_2 inhibited MAN2B2; The different downstream MAN2B2 activated ATP2B1, CCNO, OGG1_1, OGG1_2, UNG and inhibited EPHX2, GSTM3_3, INSIG1 in human left cerebrum.…”