Functionalized paper microzone plate for colorimetry and up-conversion fluorescence dual-mode detection of telomerase based on elongation and capturing amplification

Fu, An Chen; Hu, Yue; Zhao, Zihan; Su, Ruilin; Song, Yilin; Zhu, Dong

doi:10.1016/j.snb.2017.12.124

Cited by 24 publications

(8 citation statements)

References 46 publications

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Section: Chemo/bio Sensing Applicationsmentioning

confidence: 99%

“…Furthermore, the detection limit was determined to be in the subfemtomolar range. Telomerase enzymes were detected in HeLa cells extracts using a TS primer functionalized cellulose paper microzone plate (Figure D) . UCNPs were modified with TC oligonucleotide enabling their conjugation to the long single DNA produced by TS primer via telomerase reaction.…”

Section: Chemo/bio Sensing Applicationsmentioning

confidence: 99%

“…Telomerase enzymes were detected in HeLa cells extracts using a TS primer functionalized cellulose paper microzone plate (Figure 8D). 125 UCNPs were modified with TC oligonucleotide enabling their conjugation to the long single DNA produced by TS primer via telomerase reaction. This in turn led to a strong signal, which was observed to be proportional to the amount of single DNA, thereby signifying the telomerase activity.…”

Section: ■ Design Of Upconversion Nanosensorsmentioning

confidence: 99%

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Upconversion Nanoprobes: Recent Advances in Sensing Applications

et al. 2018

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Section: Chemo/bio Sensing Applicationsmentioning

confidence: 99%

Section: Chemo/bio Sensing Applicationsmentioning

confidence: 99%

Section: ■ Design Of Upconversion Nanosensorsmentioning

confidence: 99%

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Upconversion Nanoprobes: Recent Advances in Sensing Applications

et al. 2018

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“…In recent years, paper‐based colorimetric methods have been widely developed for environmental and biological analysis of various species, due to their advantages such as cost‐effectiveness, simplicity, portability and minimal sample utilization. [ 7–13 ]…”

Section: Introductionmentioning

confidence: 99%

A turn off–on fluorometric and paper‐based colorimetric dual‐mode sensor for isoniazid detection

2021

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In the present study, cobalt oxyhydroxide (CoOOH) nanosheets were applied for establishing a dual fluorometric and smartphone‐paper‐based colorimetric method to detect isoniazid. CoOOH nanosheets quenched the fluorescence emission of sulfur and nitrogen co‐doped carbon dots (S,N‐CDs) due to inner filter effect (IFE). The quenched fluorescence intensity of S,N‐CDs restored in the presence of isoniazid due to destroying CoOOH nanosheets by this drug. Moreover, with adding isoniazid the solution color of CoOOH nanosheets altered from brownish yellow to pale yellow. We exploited these facts to design a turn off–on fluorometric and paper‐based colorimetric sensor for isoniazid measurement at the range 0.5–5 and 5–100 μM with detection limits of 0.28 μM and 4.0 μM, respectively. The introduced dual sensor was used for pharmaceutical, environmental and biological analysis of isoniazid with satisfactory results. The paper‐based colorimetric sensor can be applied for isoniazid portable monitoring using a smartphone as a detector or even the naked eye.

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“…Fu et al . prepared a handle substrate of cellulose paper for telomerase with using a dual-mode method of colorimetry and upconversion fluorescence 23 . Based on the linear change of RRS intensity with the addition of Bi(III) since the reduction of Bi(III) will consume I 3 − and there was energy transfer (RRS-ET) between I 3 − and graphene oxide (GO), Liang et al .…”

Section: Introductionmentioning

confidence: 99%

A dual-model SERS and RRS analytical platform for Pb(II) based on Ag-doped carbon dot catalytic amplification and aptamer regulation

Wang

Huang

Wen

et al. 2019

Sci Rep

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Several carbon dots doping with diferent elements (Ca, Ag, Au) were fabricated and their catalytic properties had been investigated in this paper. It was found that the Ag-doped carbon dots (CD Ag ) had played a role of mimic enzyme on the reaction of HAuCl 4 -H 2 O 2 and generated nanogold particles with surface enhanced Raman scattering (SERS) and resonance Rayleigh scattering (RRS) effects. The aptamer (Apt) can be adsorbed on the CD Ag surface and cause the catalysis weakening. When the target Pb(II) was added, it would combine with the Apt to produce firm complexes Pb-Apt and desorb CD Ag , which caused its catalytic effect restore. The formed nanogold had a strong RRS peak (at 375 nm) and a high SERS peak (at 1615 cm −1 ) in the presence of molecular probe (Victoria blue B, VBB). The dual-model signals of SERS and RRS increased linearly with Pb(II) concentration increase within the scope of 0.006–0.46 μmol/L and 0.01–0.46 μmol/L. And their detection limits respectively were 0.0032 μmol/L and 0.0048 μmol/L Pb(II).

show abstract

Functionalized paper microzone plate for colorimetry and up-conversion fluorescence dual-mode detection of telomerase based on elongation and capturing amplification

Cited by 24 publications

References 46 publications

Upconversion Nanoprobes: Recent Advances in Sensing Applications

Upconversion Nanoprobes: Recent Advances in Sensing Applications

A turn off–on fluorometric and paper‐based colorimetric dual‐mode sensor for isoniazid detection

A dual-model SERS and RRS analytical platform for Pb(II) based on Ag-doped carbon dot catalytic amplification and aptamer regulation

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