Functionalized nanoparticles based solid-phase membrane micro-tip extraction and high-performance liquid chromatography analyses of vitamin B complex in human plasma
Abstract:Iron nanoparticles were prepared by a green method following functionalization using 1-butyl-3-methylimidazolium bromide. 1-Butyl-3-methylimidazole iron nanoparticles were characterized using FTIR spectroscopy, energy dispersive X-ray fluorescence, X-ray diffraction, scanning electron microscopy and transmission electron microscopy. The nanoparticles were used in solid-phase membrane micro-tip extraction to separate vitamin B complex from plasma before high-performance liquid chromatography. The optimum condit… Show more
“…The nanomaterial, that is, composite iron nanoparticles were manufactured utilizing green knowledge as defined elsewhere [32,33,34,35]. Black tea extract was mixed with ferrous sulphate solution and nanoparticles were prepared by green technology.…”
Composite nanoparticles were used in solid phase micro membrane tip extraction and capillary electrophoresis to determine phenol and p-amino-phenol in wastewater. The optimized conditions were 100 g/L concentration, 40 min contact time, 11 pH, 5 mg/mL nanoparticles amounts, 60 min desorption time, 9 desorption pH and 298 K temperature. Capillary electrophoresis conditions were phosphate buffer (15 mM, pH 7.0) background electrolyte, 18 kV applied voltage, 214 nm UV detection, 30 s sample loading at 23 ± 1 °C. The maximum percent uptakes of p-amino-phenol and phenol were 80.0 and 85.0%. High ratio recoveries of p-amino-phenol and phenol from nanomaterial were 99.0 and 98. Consequently, the actual extractions of p-amino-phenol and phenol from wastewater were 79.2 and 83.30 percent. The migration times of phenol and p-amino-phenol and were 9.0 and 12.0 min. The detection limits of phenol and p-amino-phenols were 0.1 and 0.2 µg/L after extraction and CE. Therefore, this combination of solid phase micro membrane tip extraction and capillary electrophoresis may be considered as the ideal one for monitoring of toxic phenol and p-amino-phenol in water sample.
“…The nanomaterial, that is, composite iron nanoparticles were manufactured utilizing green knowledge as defined elsewhere [32,33,34,35]. Black tea extract was mixed with ferrous sulphate solution and nanoparticles were prepared by green technology.…”
Composite nanoparticles were used in solid phase micro membrane tip extraction and capillary electrophoresis to determine phenol and p-amino-phenol in wastewater. The optimized conditions were 100 g/L concentration, 40 min contact time, 11 pH, 5 mg/mL nanoparticles amounts, 60 min desorption time, 9 desorption pH and 298 K temperature. Capillary electrophoresis conditions were phosphate buffer (15 mM, pH 7.0) background electrolyte, 18 kV applied voltage, 214 nm UV detection, 30 s sample loading at 23 ± 1 °C. The maximum percent uptakes of p-amino-phenol and phenol were 80.0 and 85.0%. High ratio recoveries of p-amino-phenol and phenol from nanomaterial were 99.0 and 98. Consequently, the actual extractions of p-amino-phenol and phenol from wastewater were 79.2 and 83.30 percent. The migration times of phenol and p-amino-phenol and were 9.0 and 12.0 min. The detection limits of phenol and p-amino-phenols were 0.1 and 0.2 µg/L after extraction and CE. Therefore, this combination of solid phase micro membrane tip extraction and capillary electrophoresis may be considered as the ideal one for monitoring of toxic phenol and p-amino-phenol in water sample.
“…There are several techniques described in the literature for extraction of drugs in biological matrices such as liquid-liquid extraction (LLE), dispersive liquid-liquid microextraction (DLLME), solid phase extraction (SPE), micro-solid-phase extraction (m-SPE), solid-phase membrane micro-tip extraction (SPMMTE), etc. [7][8][9][10] In this case, Saha and coauthors have described probe electrospray ionization mass spectrometry to detection of drugs from plasma samples with no or minimal sample pre-treatment. 11 Recent attempts in sample preparation are particularly focused on improving the quality of analytical results and introducing new technological expansions such as simplication, miniaturization and automation of the whole analytical method.…”
A sustainable nanoscale core–shell modified with hydrophobic polymeric ionic liquid was fabricated for simultaneous extraction and determination of antidiabetic drugs.
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