Functionalized manganese iron oxide nanoparticles: a dual potential magneto-chemotherapeutic cargo in a 3D breast cancer model

Abstract

Localized heat generation from manganese iron oxide nanoparticles (MIONPs) conjugated with chemotherapeutics under the exposure of alternating magnetic field (magneto-chemotherapy) can revolutionize targeted breast cancer therapy. On the other hand,...

Enhanced interfacial polarization through the conversion of Co@C into Co@Co1−xS@C nanocapsules utilizing a facile sulfidation process

“…In recent years, there has been significant progress in the development of core-shell NCs. Their excellent physical and chemical properties have attracted widespread interest in various fields, such as magnetic hyperthermia, catalysis, and EM functions [23][24][25]. In this study, we demonstrate the successful preparation of Co@Co 1−x S@C NCs through a sulfidation process using the precursor of Co@C NCs.…”

Nanomedicine as a multimodal therapeutic paradigm against cancer: on the way forward in advancing precision therapy

“…142 Likewise, these magnetic nanoparticle platforms were further expanded for more than one functionalized targeting (e.g., for anticancer agents, like doxorubicin, and tumor-targeting aptamers, like AS1411) and for high magnetization structures using diisopropylamine (reducing agent with surface stabilization properties)-based polymeric magnetic nanocarriers as a promising theranostic modality against image-guided breast cancers. 143,144 Interestingly, in 2013, Burke et al developed nanoparticles (carbon nanotubes)-mediated localized PTT against "triple negative" (HER2, estrogen, and progesterone receptors) breast cancer stem cells (CD44 high /CD24 low ) that are recognized as the most difficult to treat. The beauty of this carbon nanotube (CNT) system is its efficient antenna behavior, i.e., absorbance under electromagnetic radiation and thermal conductance.…”

“…, for anticancer agents, like doxorubicin, and tumor-targeting aptamers, like AS1411) and for high magnetization structures using diisopropylamine (reducing agent with surface stabilization properties)-based polymeric magnetic nanocarriers as a promising theranostic modality against image-guided breast cancers. 143,144…”