Functionalization and Modification of Hydrocarbon-Like Molecules Guided by Metagenomics: Enzymes Most Requested at the Industrial Scale for Chemical Synthesis as Study Cases

Biocatalysis and Biotransformations

“…Most studies reported the use of free or immobilized enzyme preparations, but whole cells transformations using cells expressing desired enzymes or new strains containing enzyme activities of interest have been also presented. Note that oxidoreductases, transferases, and hydrolases are among the three types of enzymes most used at an industrial level [1,4].…”

“…Each industrial process is different and the correct enzyme needs to be identified and/or optimized for the industrial application. Over 500 industrial products are being made using enzymes and about 150 industrial processes use enzymes or whole microbial cell catalysts [3,4]. The constant search for new enzymatic catalysts comes from the demand of constantly evolving industrial processes and the bio-economy, in which enzyme properties are appreciated.…”