Functionalization and customization of polyurethanes for biosensing applications: A state-of-the-art review

Ahmadi, Younes; Kim, Ki‐Hyun

doi:10.1016/j.trac.2020.115881

Cited by 14 publications

(7 citation statements)

References 91 publications

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“…[97] In addition, structurally and chemically modified PU could be used as the valuable media for the fabrication of implantable diagnostic electronic sensing devices. [98] Abellan et al reported a stretchable glucose biosensor based on a PU substrate for the on-body glucose determination in human perspiration. [99] The Pt-decorated graphite and Ag/AgCl electrodes that were screen-printed on the substrate showed a linear detection range up to 0.9 × 10 −3 m, a high sensitivity and selectivity, and a low detection limit.…”

Section: Synthetic Polymersmentioning

confidence: 99%

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Materials and Biomedical Applications of Implantable Electronic Devices

Liu

et al. 2022

Adv Materials Technologies

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The implantable electronic devices have attracted great attention for solving clinical problems ranging from monitoring psychological states to electro‐organ transplantation. The ongoing challenges are the selection of suitable materials in a target device configuration for biomedical applications. To address the ongoing challenges, there are several interesting questions: what types of electronic materials can be used as the implantable electrodes? What types of materials can be used as the substrates for the implantable electronic devices? What types of materials can be used as membranes and encapsulations? What types of device configurations are there for implantable biomedical applications? What types of applications are for implantable electronic devices? This review will highlight the attempts for addressing these questions. This review will explore the fundamentals and practical aspects of a variety of materials and their biomedical applications in implantable electronic devices. It is anticipated that this review could provide new opportunities for the construction of future implantable electronic devices, as well as related applications for disease diagnosis and therapy.

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Section: Synthetic Polymersmentioning

confidence: 99%

Section: Materials For the Substratementioning

confidence: 99%

Materials and Biomedical Applications of Implantable Electronic Devices

Liu

et al. 2022

Adv Materials Technologies

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“…In fact, it has been known for decades that these are most often key to rendering a sensor functional not only in pristine buffer solutions but also in the murky real-world samples, where they are supposed to function after all. Much research is hence put toward the development of new, sophisticated and customized polymers and hydrogels [74]. Also, layered and blended polymer cocktails are investigated to provide an optimal sensing environment.…”

Section: Conclusion and Future Perspectivementioning

confidence: 99%

Critical review of polymer and hydrogel deposition methods for optical and electrochemical bioanalytical sensors correlated to the sensor’s applicability in real samples

2022

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Sensors, ranging from in vivo through to single-use systems, employ protective membranes or hydrogels to enhance sample collection or serve as filters, to immobilize or entrap probes or receptors, or to stabilize and enhance a sensor’s lifetime. Furthermore, many applications demand specific requirements such as biocompatibility and non-fouling properties for in vivo applications, or fast and inexpensive mass production capabilities for single-use sensors. We critically evaluated how membrane materials and their deposition methods impact optical and electrochemical systems with special focus on analytical figures of merit and potential toward large-scale production. With some chosen examples, we highlight the fact that often a sensor’s performance relies heavily on the deposition method, even though other methods or materials could in fact improve the sensor. Over the course of the last 5 years, most sensing applications within healthcare diagnostics included glucose, lactate, uric acid, O2, H+ ions, and many specific metabolites and markers. In the case of food safety and environmental monitoring, the choice of analytes was much more comprehensive regarding a variety of natural and synthetic toxicants like bacteria, pesticides, or pollutants and other relevant substances. We conclude that more attention must be paid toward deposition techniques as these may in the end become a major hurdle in a sensor’s likelihood of moving from an academic lab into a real-world product. Graphical abstract

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“…15 PDMS is particularly favored due to its similar modulus to human tissue, chemical inertness, and non-tissue damaging properties. [16][17][18] Traditional fabrication methods of flexible tactile sensors, such as lithography, 19 screen printing, 20 and model casting, 21 have drawbacks including high cost, time-consuming processes, and challenges in preparing sensor microstructures. 22 In response, many researchers have turned to 3D printing technology to design micro and nano structures for flexible tactile sensors.…”

Section: Introductionmentioning

confidence: 99%

“…15 PDMS is particularly favored due to its similar modulus to human tissue, chemical inertness, and non-tissue damaging properties. 16–18…”

Section: Introductionmentioning

confidence: 99%

Three-dimensional printed cellulose nanofibers/carbon nanotubes/silicone rubber flexible strain sensor for wearable body monitoring

Xu,

Yue,

et al. 2024

J. Mater. Chem. C

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Functionalization and customization of polyurethanes for biosensing applications: A state-of-the-art review

Cited by 14 publications

References 91 publications

Materials and Biomedical Applications of Implantable Electronic Devices

Materials and Biomedical Applications of Implantable Electronic Devices

Critical review of polymer and hydrogel deposition methods for optical and electrochemical bioanalytical sensors correlated to the sensor’s applicability in real samples

Three-dimensional printed cellulose nanofibers/carbon nanotubes/silicone rubber flexible strain sensor for wearable body monitoring

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