Functional Status and Health-Related Quality of Life in Patients with Peripheral Artery Disease: A Cross-Sectional Study

Kim, Mihui; Kim, Yesol; Ryu, Gi Wook; Choi, Mona

doi:10.3390/ijerph182010941

Cited by 19 publications

(17 citation statements)

References 32 publications

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“…Risk factors for PAD include age, race, smoking, hypertension, diabetes, and hyperlipidemia [ 15 , 16 , 17 ]. PAD is associated with considerable physical and psychosocial disease burden, primarily resulting from impaired functional status and quality of life [ 18 , 19 , 20 , 21 , 22 ] Studies conducted in the U.S. and Hungary have highlighted that functional impairment and pain resulting from lower extremity arterial ischemia leads to reduced quality of life and, consequently, a considerable proportion of PAD patients experience severe symptoms of anxiety and depression. Studies have found that it is mainly impaired the lower extremity functioning that lies at the root of an impaired psycho-emotional state, considerably affecting engagement in social activities and family life [ 23 , 24 ].…”

Section: Introductionmentioning

confidence: 99%

Disease-Specific Quality of Life among Patients with Peripheral Artery Disease in Hungary

Horváth

Boncz

Kívés

et al. 2023

IJERPH

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Peripheral artery disease (PAD) is a progressive atherosclerotic disease significantly impacting functional status and health-related quality of life (HRQoL). This study aimed to investigate HRQoL among PAD patients in Hungary using the validated Hungarian version of the PADQoL questionnaire. Patients with symptomatic PAD were consecutively recruited from the Department of Angiology, Clinical Center, University of Pécs, Hungary. Demographics, risk factors, and comorbidities were registered. Disease severity was measured by Fontaine and WIFI stages. Descriptive statistical analysis, Chi-square test, and non-parametric tests were performed (p < 0.05). Overall, 129 patients (mean age 67.6 ± 11.9 years, men 51.9%) participated in our study. The Hungarian PADQoL demonstrated good internal consistency (α range: 0.745–0.910). Factors on intimate and social relationships gave the best (89.15 ± 20.91; 63.17 ± 26.05) and sexual function (28.64 ± 27.42), and limitations in physical functioning (24.68 ± 11.40) the worst scores. PAD had a significant negative impact on the social relationships of patients aged 21–54 years (51.6 ± 25.4). Fontaine stage IV patients experienced significantly lower HRQoL due to fear and uncertainty (46.3 ± 20.9) and limited physical functioning (33.2 ± 24.8). The Hungarian PADQoL identified central aspects of HRQoL. Advanced PAD was found to impact several areas of HRQoL, primarily physical functioning and psycho-social well-being, drawing attention to the importance of early diagnosis and management.

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Section: Introductionmentioning

confidence: 99%

Disease-Specific Quality of Life among Patients with Peripheral Artery Disease in Hungary

Horváth

Boncz

Kívés

et al. 2023

IJERPH

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“…Peripheral artery disease (PAD) is a cardiovascular disease, characterized by walking difficulties due to intermittent claudication defined by leg muscle pains, fatigue, or cramping induced by exercise or ambulation, and its prevalence rising with age [ 1 , 2 ]. Notably, declined functional status and PAD-related symptoms are associated with poorer health-related quality of life [ 2 , 3 ]. PAD prognosis can be improved by risk factor modification through revascularization, medication, and exercise therapy [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

Mobile health platform based on user-centered design to promote exercise for patients with peripheral artery disease

Kim

Choi

2022

BMC Med Inform Decis Mak

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Background Peripheral artery disease (PAD) is a cardiovascular disease that can be improved by risk factor modification. Mobile health (mHealth) intervention is an effective method of healthcare delivery to promote behavior changes. An mHealth platform can encourage consistent involvement of participants and healthcare providers for health promotion. This study aimed to develop an mHealth platform consisting of a smartphone application (app) synchronized with a wearable activity tracker and a web-based portal to support exercise intervention in patients with PAD. Methods This study was conducted based on an iterative development process, including analysis, design, and implementation. In the analysis phase, a literature review and needs assessment through semi-structured interviews (n = 15) and a questionnaire-based survey (n = 138) were performed. The initial prototype design and contents were developed based on the users’ requirements. In the implementation phase, multidisciplinary experts (n = 4) evaluated the heuristics, following which the mHealth platform was revised. User evaluation of the usability was performed by nurses (n = 4) and patients with PAD (n = 3). Results Through the development process, the functional requirements of the platform were represented through visual display, reminder, education, self-monitoring, goal setting, goal attainment, feedback, and recording. In-app videos of exercise and PAD management were produced to provide information and in-app automatic text messages were developed for user motivation. The final version of the platform was rated 67.86 out of 100, which indicated “good” usability. Conclusions The mHealth platform was designed and developed for patients with PAD and their healthcare providers. This platform can be used to educate and promote individualized exercise among patients with PAD.

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“…Furthermore, chronic diseases such as PAD affect psychological well-being by inducing depression, anxiety, and low quality of life [ 20 , 21 ]. Pain and difficulty in walking distances and climbing stairs in patients with PAD are significantly related to quality of life [ 22 ] and well-being [ 23 ].…”

Section: Introductionmentioning

confidence: 99%

Incidence and Prevalence of Peripheral Arterial Disease in South Korea: Retrospective Analysis of National Claims Data

Ryu¹,

Park²,

Kim³

et al. 2022

JMIR Public Health Surveill

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Background Peripheral arterial disease (PAD) causes blood vessel narrowing that decreases blood flow to the lower extremities, with symptoms such as leg pain, discomfort, and intermittent claudication. PAD increases risks for amputation, poor health-related quality of life, and mortality. It is estimated that more than 200 million people worldwide have PAD, although the paucity of PAD research in the East detracts from knowledge on global PAD epidemiology. There are few national data–based analyses or health care utilization investigations. Thus, a national data analysis of PAD incidence and prevalence would provide baseline data to enable health promotion strategies for patients with PAD. Objective This study aims to identify South Korean trends in the incidence and prevalence of PAD and PAD treatment, in-hospital deaths, and health care utilization. Methods This was a retrospective analysis of South Korean national claims data from 2009 to 2018. The incidence of PAD was determined by setting the years 2010 and 2011 as a washout period to exclude previously diagnosed patients with PAD. The study included adults aged ≥20 and <90 years who received a primary diagnosis of PAD between 2011 and 2018; patients were stratified according to age, sex, and insurance status for the incidence and prevalence analyses. Descriptive statistics were used to assess incidence, prevalence, endovascular revascularization (EVR) events, amputations, in-hospital deaths, and the health care utilization characteristics of patients with PAD. Results Based on data from 2011 to 2018, there were an average of 124,682 and 993,048 incident and prevalent PAD cases, respectively, in 2018. PAD incidence (per 1000 persons) ranged from 2.68 to 3.09 during the study period. From 2012 to 2018, the incidence rate in both sexes showed an increasing trend. PAD incidence continued to increase with age. PAD prevalence (per 1000 persons) increased steadily, from 3.93 in 2011 to 23.55 in 2018. The number of EVR events varied between 933 and 1422 during the study period, and both major and minor amputations showed a decreasing trend. Health care utilization characteristics showed that women visited clinics more frequently than men, whereas men used tertiary and general hospitals more often than women. Conclusions The number of incident and prevalent PAD cases generally showed an increasing trend. Visits to tertiary and general hospitals were higher among men than women. These results indicate the need for attention not only to Western and male patients, but also to Eastern and female patients with PAD. The results are generalizable, as they are based on national claims data from the entire South Korean population, and they can promote preventive care and management strategies for patients with PAD in clinical and public health settings.

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Functional Status and Health-Related Quality of Life in Patients with Peripheral Artery Disease: A Cross-Sectional Study

Cited by 19 publications

References 32 publications

Disease-Specific Quality of Life among Patients with Peripheral Artery Disease in Hungary

Disease-Specific Quality of Life among Patients with Peripheral Artery Disease in Hungary

Mobile health platform based on user-centered design to promote exercise for patients with peripheral artery disease

Incidence and Prevalence of Peripheral Arterial Disease in South Korea: Retrospective Analysis of National Claims Data

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