Functional results one-year following the anti-VEGF therapy in macular pathology

Abstract

This investigation aims at evaluating the functional results 1-year following anti-VEGF therapy in macular pathology. Material and method: This is a retrospective examination that was carried out on 57 patients with macular pathology out of 108 at Sf. Spiridon Hospital in Iasi. 57 patients with macular pathology were included in the investigation, respectively 57 eyes, 24 eyes with diabetic macular edema and 33 with neovascular age-related macular degeneration. Eyes in which less than 6 intravitreous injections were performed (less than one-year of follow-up) as well as those without oct control examinations and without adequate controls were excluded. Results: Visual acuity improves considerably after the therapy was performed in both patients experiencing diabetic macular edema (370 vs 320 microns) and in those with age-related macular degeneration (320 vs 260 microns), while the average thickness of the central macula decreases considerably after therapy. Conclusions: In this study, the therapy with intravitreal Aflibercept was associated with improving the functional and anatomical outcomes, keeping the increasing trend up to one-year of therapy in those who received a minimum of three injections.